Strain Dependency of the Immunopotentiating Activity of Lactobacillus delbrueckii subsp. bulgaricus
スポンサーリンク
概要
- 論文の詳細を見る
To obtain strains of Lactobacillus delbrueckii subsp. bulgaricus with high immunopotentiating activity, we screened 90 strains of this bacterial species for the proliferative response of murine spleen and β-lactoglobulin-primed lymph node cells. In this screening, certain strains showed strong immunopotentiating activity. Among them, strain 1023 had the strongest mitogenic activity for murine Peyer's patch (PP) cells. Furthermore, strain 1023 induced IgA antibody production by PP cells as strongly as Bifidobacterium longum 6001,which had adjuvant activity when orally administered. Also in the assays using immune cells from human-flora-associated mice a few strains including 1023 showed strong immunopotentiating activity comparable to B. longum 6001. These results suggest that L. delbrueckii subsp. bulgaricus strains such as 1023 may be useful for the production of fermented milk with a more beneficial effect on the systemic and mucosal immune system.
- 社団法人日本農芸化学会の論文
- 1999-03-23
著者
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ITOH Kikuji
Department of Veterinary Public Health, Graduate School of Agricultural and Life Sciences, Universit
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Yajima Takaji
Nutrition Science Institute Meiji Milk Products Co. Ltd.
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Yajima Takaji
Nutrition Science Institute Meiji Milk Products Co. Ltd. Odawara Japan
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Takahashi T
Department Of Sustainable Resource Science Faculty Of Bioresources Mie University
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Tsushida T
National Food Res. Inst. Tsukuba Jpn
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Tsushida Tojiro
National Research Institute Of Vegetables Ornamental Plants And Tea Department Of Tea Processing Tec
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Itoh Kikuji
Department Of Veterinary Medicine Graduate School Of Agricultural And Life Sciences The University O
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Itoh K
Graduate School Of Pharmaceutical Sciences Chiba University:nisshin Seifun Group Inc.
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NAGAFUCHI Shinya
Nutrition Science Institute, Meiji Milk Products Co., Ltd.
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TAKAHASHI Takeshi
Nutrition Science Institute, Meiji Milk Products Co., Ltd.
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KUWATA Tamotsu
Nutrition Science Institute, Meiji Milk Products Co., Ltd.
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HIRAYAMA Kazuhiro
Department of Veterinary Public Health, Faculty of Agriculture, The University of Tokyo
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Kuwata T
Meiji Dairies Corp. Tokyo Jpn
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Kuwata Tamotsu
Applied Alimentary Technology Research Department Nutrition Science Institute Meiji Milk Products Co
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Kuwata Tamotsu
Nutrition Science Institute Meiji Milk Products Co. Ltd.
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Nagafuchi Shinya
Nutrition Science Institute Meiji Milk Products Co. Ltd.:department Of Applied Biological Chemistry
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Hirayama K
Department Of Veterinary Public Health Faculty Of Agriculture The University Of Tokyo
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Hirayama Kazuhiro
Department Of Veterinary Public Health
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Hirayama Kazuhiro
Department Of Medical Nutrition Karolinska Institutet
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Takahashi Takeshi
Nutrition Science Institute Meiji Milk Products Co. Ltd.
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