Mioga (Zingiber mioga Rosc.) Extract Prevents 3T3-L1 Differentiation into Adipocytes and Obesity in Mice
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概要
- 論文の詳細を見る
We examined the effect of edible plant extracts on prevention of obesity. 3T3-L1 cell that differentiated into a mature adipocyte was used as a model for screening in vitro. After the cells had formed a confluent monolayer, they were treated with DEX-MIX and incubated in a medium containing edible plant extract for 12 days. The mioga (Zingiber mioga Rosc.) extract significantly suppressed the increase in glycerol-3-phosphate dehydrogenase activity and triglyceride accumulation in 3T3-L1 cells. The results of Oil-Red O staining supported these findings. We further investigated the effect of mioga extract in prevention of obesity in male ICR mice in vivo. Through oral administration of the extract (10 or 50 mg/mouse), increases in body weight and epididymal fat weight were prevented in the animals. These results indicate that mioga extract may be useful in preventing obesity.
- 社団法人 日本食品科学工学会の論文
- 2001-05-01
著者
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Takahashi T
Department Of Sustainable Resource Science Faculty Of Bioresources Mie University
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Tsushida T
National Food Res. Inst. Tsukuba Jpn
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Tsushida Tojiro
National Food Research Institute
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Tsushida Tojiro
National Research Institute Of Vegetables Ornamental Plants And Tea Department Of Tea Processing Tec
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YAMAKI Kohji
National Agricultual Research Center for Tohoky Region
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IWASHITA Keiko
Institute of Applied Biochemistry, University of Tsukuba
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Yamaki K
National Agricultual Res. Center For Tohoku Region Fukushima Jpn
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Isshiki K
Institute Of Applied Biochemistry University Of Tsukuba
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Tsushida Tojiro
National Food Res. Inst. Tsukuba Jpn
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