Development of Intestinal Flora of Human-Flora-Associated (HFA) Mice in the Intestine of their Offspring
スポンサーリンク
概要
- 論文の詳細を見る
Development of intestinal flora in newborn human-flora-associated (HFA) mice was compared with that in newborn conventional (CV) mice. Facultative anaerobes were detected from the first day after birth in both CV and HFA mice but anaerobes were not detected in the first week. Anaerobes rapidly increased from the 2nd week after birth and became predominant in newborn intestine. Most of the intestinal bacteria in adult CV and HFA mice were colonized in the intestine of CV and HFA mice, respectively, within 3 weeks after birth. The human intestinal flora established in the intestine of HFA mice finally reproduced without any remarkable change in composition in the intestine of newborn HFA mice. The development of intestinal flora in HFA mice was similar to that in CV mice but not that in human infants. These results indicated that human flora associated in HFA mice could be transferred from mothers to their offspring although HFA mice could not simulate the development of intestinal flora of the human infant.
- 社団法人 日本実験動物学会の論文
著者
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TAKAHASHI Eiji
Department of Ocean Sciences, Tokyo University of Marine Science and Technology
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ITOH Kikuji
Department of Veterinary Public Health, Graduate School of Agricultural and Life Sciences, Universit
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KAWAMURA Seiji
Department of Biomedical Science, Graduate School of Agricultural and Life Sciences, the University
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Mitsuoka Tomotari
Department of Food Hygiene, Nippon Veterinary and Animal Science University
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Mitsuoka Tomotari
Department Of Biomedical Science Faculty Of Agriculture The University Of Tokyo
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Itoh Kikuji
Department Of Veterinary Medicine Graduate School Of Agricultural And Life Sciences The University O
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HIRAYAMA Kazuhiro
Department of Veterinary Public Health, Faculty of Agriculture, The University of Tokyo
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HIRAYAMA Kazuhiro
Graduate School of Agricultural and Life Sciences, The University of Tokyo
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Hirayama Kazuhiro
Graduate School Of Agricultural And Life Sciences The University Of Tokyo
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Miyaji Kazuhiro
Department Of Biomedical Science Faculty Of Agriculture The University Of Tokyo
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Takahashi Eiji
Department Of Biology Faculty Of Science Kobe University
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Hirayama Kazuhiro
Department Of Medical Nutrition Karolinska Institutet
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Kawamura Seiji
Department Of Biomedical Science Faculty Of Agriculture The University Of Tokyo
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Kawamura Seiji
Department Of Biomedical Science Faculty Of Agriculture And Life Sciences University Of Tokyo
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KAWAMURA Seiji
Department of Agriculture, The University of Tokyo
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Takahashi Eiji
Department of Applied Chemistry, Faculty of Engineering, Kanagawa University
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