Senile Plaques in an Aged Western Lowland Gorilla
スポンサーリンク
概要
- 論文の詳細を見る
Senile plaques (SPs) were found in the cerebral cortex of a 44-year-old Western lowland gorilla (Gorilla gorilla gorilla). All the SPs were obtained as dense assemblies consisting of fibrous materials by silver impregnation, but were not detected by Congo red. More SPs were detected by immunostaining for amyloidb protein (Aβ) and a half of Aβ-positive-SPs were also immunoreactive for apolipoprotein E. Moreover, all SPs were immunoreactive for Aβ 42 and Aβ 43, but not for Aβ 40. SPs also did not contain Aβ precursor protein-positive structures. These findings suggested that SPs in this case were diffuse plaques. To our knowledge, this is the first report of SPs in the gorilla.
- 社団法人 日本実験動物学会の論文
著者
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YOSHIKAWA Yasuhiro
Department of Biomedical Science, Graduate School of Agricultural and Life Sciences, The University
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KIMURA Nobuyuki
Department of Biomedical Science, Graduate School of Agricultural and Life Sciences, the University
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KAWAMURA Seiji
Department of Biomedical Science, Graduate School of Agricultural and Life Sciences, the University
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Kawamura Seiji
Department Of Biomedical Science Graduate School Of Agricultural And Life Sciences The University Of
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Nakamura Shinichiro
Department Of Veterinary Pathology Nippon Veterinary And Animal Science University
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Yoshikawa Yasuhiro
Department Of Biomedical Science Graduate School Of Agricultural And Life Sciences The University Of
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Kimura Nobuyuki
Department Of Biomedical Science Graduate School Of Agricultural And Life Sciences University Of Tok
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Yoshikawa Yasuhiro
Department Of Biomedical Science Faculty Of Agriculture The University Of Tokyo
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Hayashi Takako
Animal Hospital Ueno Zoological Gardens
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Goto N
Shin-nihon Kagaku Tokyo Pathology Center
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GOTO Naoaki
Shin-nihon Kagaku, Tokyo Pathology Center
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NARUSHIMA Etsuo
Animal Hospital, Ueno Zoological Gardens
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HARA Itsuko
Animal Hospital, Ueno Zoological Gardens
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SHICHIRI Shigemi
Animal Hospital, Ueno Zoological Gardens
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SAITOU Kazuo
Animal Hospital, Ueno Zoological Gardens
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NOSE Masao
Animal Hospital, Ueno Zoological Gardens
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Nakamura Shinichiro
Department Of Orthopaedic Surgery Graduate School Of Medicine Chiba University
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Shichiri Shigemi
Animal Hospital Ueno Zoological Gardens
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Hara Itsuko
Animal Hospital Ueno Zoological Gardens
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Saitou Kazuo
Animal Hospital Ueno Zoological Gardens
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Nose Masao
Animal Hospital Ueno Zoological Gardens
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Kawamura Seiji
Department Of Biomedical Science Graduate School Of Agricultural And Life Sciences The University Of
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Kawamura Seiji
Department Of Biomedical Science Faculty Of Agriculture And Life Sciences University Of Tokyo
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Nakamura Shinichiro
Department Of Gastroenterology And Hepatology Okayama University Graduate School Of Medicine Dentist
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NAKAMURA Shinichiro
Department of Gastroenterology & Hepatology, Okayama University Graduate School of Medicine and Dentistry, Okayama
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Nakamura Shinichiro
Department of Electronic Engineering, Graduate School of Engineering, Tohoku University
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KAWAMURA Seiji
Department of Agriculture, The University of Tokyo
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