A New Screening Method for the Selection of Lactobacillus acidophilus Group Lactic Acid Bacteria with High Adhesion to Human Colonic Mucosa

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概要

• 論文の詳細を見る

• A hemagglutination (HA) assay was done for the screening of lectin-like components in surface layer protein (SLP) from Lactobacillus (L.) acidophilus A group strains. The new screening method, using polystyrene beads coated with rat-colonic mucin (RCM), which combines sugar chains similar to those of human colonic mucin, was also done. The results showed that the HA assay was not a good indicator for selecting strains having high adhesion to the human intestinal tract. The SLPs from 3 strains that strongly bound to RCM also bound well to carbohydrate portions of Carnoy's-fixed human colonic mucous layer. These results suggest that this method is a new promising screening technique for the L. acidophilus strains having high adhesion to the human intestinal tract.

• 社団法人日本農芸化学会の論文
• 1996-09-23

著者

• SAITO Tadao

  Laboratory of Animal Products Chemistry, Graduate School of Agricultural Science, Tohoku University

• Itoh Tomoyuki

  Department Of Biological Mechanisms And Functions Graduate School Of Bioagricultural Sciences Nagoya

• OHWADA Shyuichi

  Laboratory of Functional Morphology, Department of Animal Science, Graduate School of Agricultural S

• ITOH Takatoshi

  Laboratory of Animal Food Science, College of Bioresource Science, Nihon University

• OTA Hiroyoshi

  Department of Laboratory Medicine, Shinshu University School of Medicine

• Ota Hiroyoshi

  Department Of Biomedical Laboratory Sciences School Of Health Sciences Shinshu University School Of

• Ota Hiroyoshi

  Department Of Laboratory Medicine Shinshu University School Of Medicine

• Itoh T

  Laboratory Of Animal Food Science College Of Bioresource Science Nihon University

• Itoh T

  Faculty Of Agriculture Iwate University

• Itoh T

  Hiroshima Univ. Higashi-hiroshima Jpn

• TAKAHASHI Noritoshi

  Laboratory of Animal Products Chemistry, Department of Applied Bio-Science, Faculty of Agriculture,

• HASHIBA Honoh

  Technical Research Institute, Snow Brand Milk Products Co., Ltd.

• Ohwada Shyuichi

  Laboratory Of Functional Morphology Department Of Applied Bio-science Faculty Of Agriculture Tohoku

• Ohwada Shyuichi

  Laboratories Of Animal Breeding And Animal Morphology

• Hashiba Honoh

  Technical Research Institute Snow Brand Milk Products Co. Ltd.

• Takahashi Noritoshi

  Laboratory Of Animal Products Chemistry Department Of Applied Bio-science Faculty Of Agriculture Toh

• Saito Tadao

  Laboratory Of Animal Products Chemistry Graduate School Of Agricultural Science Tohoku University

• Ota Hiroyoshi

  Department Of Biomedical Laboratory Sciences School Of Health Sciences Shinshu University

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