SHRSPの血圧, 寿命および脳卒中の発症におよぼす高血圧状態からの2,3のビタミン投与の影響

概要

論文の詳細を見る
From hypertensive stage that blood pressure showed 230 mmHg or over, stroke-prone spontaneously hypertensive rats (SHRSP) were fed on several vitamin diets, and the effects of vitamins on the blood pressure, stroke incidence rate and life-span were observed. As vitamins, riboflavin (VB_2), L-ascorbic acid (VC) and α-tocopherol (VE) were used. Both the groups of VB_2 and VC did not show to affect blood pressure, stroke incidence rate and life- span, but in VE group the reduction in incidence of cerebrovascular lesion and the elongation of life-span without a fall in blood pressure were recognized. The lipid peroxide level (TBARS value) in serum of the control group showed marked increase after 10 weeks of age, but in the VE group the level remained almost unchanged. The levels of TBARS in the both group VB_2 and group VC were somewhat lower than those in the control group. These results suggest that VE diet may make the hypertensive prognosis favorable.
近畿大学の論文
1987-12-30