Subcapsular Cell Hyperplasia and Mast Cell Infiltration in the Adrenal Cortex of Mice: Comparative Study in 7 Inbred Strains
スポンサーリンク
概要
- 論文の詳細を見る
Subcapsular cell hyperplasia (SCH) in the adrenal cortex of aged mice (13-15 months old) was frequent in both sexes of BALB/c, C3H/He, DBA/2J and IQI/Jic mice and in the females of A/J and C57BL/6, although the incidence and severity of SCH were considerably different among mouse strains. Mast cells were closely associated with SCH in the A/J, BALB/c, C57BL/6, DBA/2J and IQI/Jic mice, but not in the C3H/He strain. Compared with other strains, IQI/Jic mice had a significantly larger number of mast cells in the adrenal glands. Our findings suggest that mast cells may participate in the development of SCH, and IQI/Jic would be suitable for studying the pathogenesis of SCH and the role of mast cells in this lesion.
- 社団法人 日本実験動物学会の論文
- 1997-10-01
著者
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Doi Kunio
Department of Veterinary Pathology, Faculty of Agriculture, The University of Tokyo
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Shinozuka Junko
田辺三菱製薬
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Doi Kunio
Department Of Applied Chemistry Nagoya Institute Of Technology
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Kim Jong-soo
Laboratory Of Experimental Toxicology National Institute Of Industrial Health
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KUBOTA Hisayo
National Institute of Industrial Health
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KUBOTA Hisayo
Laboratory of Experimental Toxicology, National Institute of Industrial Health
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KIUCHI Yoshihiro
Laboratory Animal Facility, School of Medicine, Yokohama City University
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SAEGUSA Junzo
Laboratory of Experimental Toxicology, National Institute of Industrial Health
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Doi K
Univ. Tokyo Tokyo Jpn
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Doi K
Faculty Of Agriculture The University Of Tokyo
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Saegusa J
National Inst. Industrial Health Kawasaki Jpn
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Saegusa Junzo
National Institute Of Occupational Safety And Health
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Saegusa Junzo
Department Of Human Engineering National Institute Of Industrial Health
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Saegusa Junzo
Laboratory Of Experimental Toxicology National Institute Of Industrial Health
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Kubota H
Laboratory Of Experimental Toxicology National Institute Of Industrial Health
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Kubota Hisayo
Laboratory Of Experimental Toxicology National Institute Of Industrial Health
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Kiuchi Y
Laboratory Animal Facility School Of Medicine Yokohama City University
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