Lectinhistochemistry of Dorsal Skin of Wistar-derived Hypotrichotic WBN/Ila-Ht Rats
スポンサーリンク
概要
- 論文の詳細を見る
A lectin histochemical study was carried out on the dorsal skin of Wistar-derived hypotrichotic WBN/Ila-Ht rats (HtRs) and Wistar rats (WRs) at 3, 7 and 24 weeks of age to clarify the lectinhistochemical characteristics of the skin during their development. The lectins examined were Concanavalia ensiformis (Con A), Dolichos biflorus agglutinin (DBA), Griffonia simpliciolia (GS-I), Helix pomatia agglutinin (HPA), Arachis hypogaea (PNA), Glycine maximus agglutinin (SBA), Ulex europeus agglutinin (UEA-I) and Triticum vulgaris agglutinin (WGA). None of the nucleated cell layers of the epidermis had DBA-binding sites, but they were all stained intensely with HPA and weakly with Con A irrespective of the strain and age of the rats. As to the other 5 lectins, the intensity of binding activity was generally weaker in HtRs than in WRs and at 3 weeks of age than at 7 or 24 weeks of age, respectively. Among them, UEA-I mainly bound to the spinous cell layer but not to the basal cell layer, suggesting that α-L-fucose would be expressed on the cell surface according to the differentiation of keratinocytes. In addition, GS-I, HPA and UEA-I bound to the hair follicle epithelium and many lectins stained sebaceous gland epithelial cells. In conclusion, except for the binding intensity of some lectins, there were no specific differences between HtRs and WRs in the lectinhistochemical characteristics of the dorsal skin epidermis. The present data on the rat skin would be useful from the viewpoint of comparative lectinhistochemistry.
- 社団法人 日本実験動物学会の論文
著者
-
Doi K
Department Of Veterinary Pathology Faculty Of Agriculture The University Of Tokyo
-
土井 邦雄
残留農薬研究所
-
Nakayama H
Department Of Veterinary Pathology Graduate School Of Agricultural And Life Sciences University Of T
-
Doi Kunio
Department of Veterinary Pathology, Faculty of Agriculture, The University of Tokyo
-
NAKAYAMA Hiroyuki
Department of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, The Universit
-
UETSUKA Koji
Department of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, The Universit
-
Nakayama H
Dep. Of Veterinary Pathology Graduate School Of Agricultural And Life Sciences The Univ. Of Tokyo
-
Nakayama Hiroyuki
Department Of Internal Medicine And Therapeutics Osaka University Graduate School Of Medicine
-
Doi Kunio
日本生物科学研究所
-
Doi Kunio
Department Of Applied Chemistry Nagoya Institute Of Technology
-
Uetsuka K
Univ. Tokyo Tokyo
-
Uetsuka Koji
Department Of Veterinary Pathology Faculty Of Agriculture The University Of Tokyo
-
IWAMOTO Shoko
Department of Veterinary Pathology, Faculty of Agriculture, The University of Tokyo
-
土居 千代
Department Of Veterinary Pathology Faculty Of Agriculture The University Of Tokyo
-
DOI Chiyo
Department of Veterinary Pathology, Faculty of Agriculture, The University of Tokyo
-
Uetsuka K
Department Of Veterinary Pathology Faculty Of Agriculture The University Of Tokyo
-
Iwamoto Shoko
Department Of Veterinary Pathology Faculty Of Agriculture The University Of Tokyo
-
Nakayama Hiroyuki
Department Of Veterinary Pathology Faculty Of Agriculture The University Of Tokyo
関連論文
- Differences in bone responses to recombinant human granulocyte colony-stimulating factor between mice and rats
- Involvement of Sex, Strain and Age Factors in High Fat Diet-Induced Obesity in C57BL/6J and BALB/cA Mice
- Depressive effects of immunosuppressant and anti-inflammatory drugs on HgCl_2-induced inflammatory lesions in Brown Norway rat(Immune system, Allergy, Proceedings of the 32nd Annual Meeting)
- MMP/TIMP activities in DMBA-induced rat mammary gland tumors(Mutagenicity, Carcinogenicity, Proceedings of the 32nd Annual Meeting)
- Induction of Cytochrome P450 isozymes by phenobarbital in pregnant rat and fetal livers and placenta(Drug metabolism, Proceedings of the 32nd Annual Meeting)
- Recovery from pregnancy-induced down-regulation of cytochrome P450 isozymes (CYPs) protein levels in postpartum rat liver(Proceedings of the 32nd Annual Meeting)
- Histopathological changes in the brain of mouse fetuses by etoposide-administration(Proceedings of the 32nd Annual Meeting)
- DNA damage-induced toxicity and repair system in the developing fetal brain(Analysis of Toxicological Mechanisms : A Toxicogenomics Approach, Proceedings of the 32nd Annual Meeting)
- Age-Dependent Susceptibility to MPTP Neurotoxicity in C57BL Mice : A Tyrosine Hydroxylase-Immunohistochemical Evaluation
- The Susceptibility of Pregnant Mice to Encephalomyocarditis (EMC) Virus Infection on Different Days of Gestation
- 1-β-D-Arabinofuranosylcytosine (Ara-C)-induced Apoptosis in the Rat Fetal Tissues and Placenta
- Gene Expression Profiles in the Liver, Placenta and Fetal Liver in Pregnant Rats Treated with T-2 Toxin (TOXICOGENOMICS AND TOXICOPROTEOMICS) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
- DNA Damages and Changes in Proliferating Activity in the Dorsal Epidermis of UVB-Irradiated WBN/ILA-Ht Rats
- T-2 Toxin-Induced Morphological Changes in Pregnant Rats
- Effects of Exogenous Growth Hormone (GH)-Treatment on Carbon Tetrachloride (CCl_4)-Induced Acute Liver Injury in GH-Deficient Mini Rats
- Effects of T-2 Toxin on the Expression of Connexin 32 in the Mouse Liver
- Effects of T-2 Toxin Treatment on CCl_4-Induced Hepatic Necrosis in Mice
- Liver Responses to Repeated Doses of Carbon Tetrachloride in Mini and Wistar Rats
- O11-07 The Effects of Formaldehyde Inhalation on the Responses to Allergen Challenge in Brown Norway and Fischer 344 Rats
- P-49 Nivalenol-Induced Apoptosis in Lymphoid Organs of Mice.(Proceedings of the 27th Annual Meeting)
- P-48 Regulation of contact hypersensitivity in BALB/c mice repeatedly elicited with picryl-chloride.(Proceedings of the 27th Annual Meeting)
- Immunohistochemical detection of PTHrP and PTH/PTHrP receptor 1 on the odontoblastic reparative process after actinomycin D treatment in rats(Liver, Alimentary system, Proceedings of the 32nd Annual Meeting)
- Teratologic Studies on Rat Perinates and Offspring from Dams Treated with Ethylnitrosourea (ENU)
- Tissue Distribution and Sequence of T-2 Toxin Induced-Apoptosis
- Changes in Location and Number of Tartrate-Resistant Acid Phosphatase (TRAP)-Positive Cells During the Development of Type II Collagen-Induced Arthritis in DBA/1J Mice
- Application of Flash and Cumulative Labeling with Bromodeoxyuridine for Analysis of Cell Kinetics of Bone Cells and Chondrocytes in Young Growing Rats
- Immunohistochemical Study on Type II Collagen-Induced Arthritis in DBA/1J Mice
- Immunohistochemical Study on Galactosamine-Induced Subacute Hepatitis in Rats of JCL: Wistar-TGN (ARGHGEN) 1Nts Strain (Mini rats)
- D-Galactosamine Induced Hepatocyte Apoptosis is Inhabited in vivo and in Cell Culture by a Calcium Calmodulin Antagonist, Chlorpromazine, and a Calcium Channel Blocker, Verapamil
- Aortic Atheromatous Lesions Developed in APA Hamsters with Streptozotocin induced Diabetes: A New Animal Model for Diabetic Atherosclerosis. 1. Histopathological Studies
- P6-52 Gene expression analysis in mouse primary cultured hepatocytes exposed to streptozotocin(TOXICOGENOMICS)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
- Immunohistochemical Study on the Deposition of Apolipoprotein E in Cerebral and Islet Amyloidoses in Cynomolgus Monkeys (Macaca fascicularis)
- Immunohistochemical detection of anti-oxidative stress enzymes in the dog brain
- Immunohistochemical detection of tau protein in various non-human animal brains
- テオフィリンを反復投与したF344ラットにおける顎下腺の遺伝子発現の変化
- Changes in Salivary Gene Expression in F344 Rats Exposed to Theophylline
- Gene expression changes induced by theophylline in the salivary glands of rats(Proceedings of the 32nd Annual Meeting)
- Nitrofurazone-induced changes in the rat liver(Proceedings of the 32nd Annual Meeting)
- Immunohistochemical Detection of PTHrP and PTH/PTHrP Receptor 1 on the Odontoblastic Reparative Process after Actinomycin D Treatment in Rats
- Morphological Changes in Salivary Glands Induced by Theophylline in Rats
- Endothelial Hypertrophy in Acute Phase of Arteritis Induced by Fenoldopam, a Vasodilator, in Rats
- RESTITUTIVE RESPONSE OF MINI RAT LIVER TO INJURY INDUCED BY A SINGLE ORAL ADMINISTRATION OF THIOACETAMIDE
- Early Ultrastructural Changes in the Dorsal Skin Epidermis of W5istar-Derived Hypotrichotic WBN/ILA-Ht Rats after UVB-Irradiation
- T-2 Toxin-Induced Apoptosis and c-fos mRNA Expression in Con A-Stimulated Mouse Thymocyte Primary Cultures
- 5-Azacytidine-induced Apoptosis in Lymphoid and Hematopoietic Organs of Adult Mice
- Renal Tubulointerstitial Lesions in Mercuric Chloride—Treated F344 Rats
- The Combination of Fixation Using PLP Fixative and Embedding in Paraffin by the AMeX Method is Useful for Immunohistochemical and Enzyme Histochemical Studies of the Lung
- 21C-02-1 Hepatic microsomal drug-metabolizing enzymes in male Nts:Minirats: cytochrome P450s and flavin-containing monooxygenase 1 (FMO1).
- Age-Related Changes in Susceptibility of Mice to Low-Virulent Mouse Hepatitis Virus (MHV-2-CC) Infection
- Electron Microscopic Study of Subcapsular Cell Hyperplasia in the Adrenal Glands of IQI/Jic Mice
- Subcapsular Cell Hyperplasia and Mast Cell Infiltration in the Adrenal Cortex of Mice: Comparative Study in 7 Inbred Strains
- Correlation of Mast Cells with Spindle Cell Hyperplasia in the Adrenal Cortex of IQI/Jic Mice
- Sequence of and Regional Difference in Apoptotic Index in the Mouse Gastrointestinal Mucous Epithelia after T-2 Toxin Inoculation
- Rapid Induction of Liver Cirrhosis in Mini Rats by Thioacetamide
- A Further Comparative Study on Early Histological Changes in Respiratory Tract of Brown Norway and Fischer 344 Rats after Short-Term Inhalation of Formaldehyde Aerosol
- Comprehensive analysis of hepatic gene and protein expression profiles on phenobarbital- or clofibrate-induced hepatic hypertrophy in dogs
- Comparative Study on Picryl Chloride (PCL)-Induced Contact Dermatitis in Female IQI/Jic and BALB/c Mice
- The Role of CD4^+ T Cells in Biphasic Hind Limb Paralysis Induced by the D Variant of Encephalomyocarditis Virus (EMC-D) in DBA/2 Mice
- Histological Characteristics of Respiratory System in Brown Norway Rat
- Nitrofurazone at a High Dose Induces Hepatocyte and Adrenal Necrosis in Rats
- Age-Related Histochemical and Ultrastructural Changes in Renal Glomerular Mesangium of APA Hamsters
- Ultrastructure of the Dorsal Skins of Hairless Descendants Derived from Mexican Hairless Dogs
- Dermal Histology of Hairless Rat Derived from Wistar Strain
- EFFECTS OF T-2 TOXIN ON HEPATOCYTE PROLIFERATION IN NORMAL MICE
- Detection of Viral RNA by Electron Microscopic In situ Hybridization (ISH-EM) in The Germinal Epithelium of Mice Infected with Encephalomyocarditis (EMC) Virus
- Variation in Serum Creatine Phosphokinase Activity as Indicated in Two-Phase EMC-D Virus-Induced Myocarditis
- Involvement of Macrophages in the Development of Encephalomyocarditis (EMC) Virus-Induced Diabetes in Mice
- T-2 Toxin and Apoptosis
- Hydrogen Peroxide-Induced Dermatitis in WBN/Kob-Ht Rats
- Development of Apoptosis and Changes in Apoptosis-related Genes Expression in the Mouse Thymus Following T-2 Toxin-inoculation
- T-2 Toxin Induced Skin Lesions in Hipotrichosis (Ht) Rats
- 5-Azacytidine-induced Apoptosis in the Central Nervous System of Developing Rat Fetuses
- Process of the Development of T-2 Toxin-induced Apoptosis in the Lymphoid Organs of Mice
- "A-15 Sequence of T-2 toxin- induced apoptosis in the lymphoid organs of mice
- "A-6 Immunohistochemical study on the component cells and extracellular matrix in galactosamine- induced acute hepatitis in rats.
- Environmental Effect on Eosinophilic Granulomatous Pneumonia (EGP) in Brown Norway Rats
- Glycoconjugate Expression in Follicle-Associated Epithelium (FAE) Covering the Nasal-Associated Lymphoid Tissue (NALT) in Specific Pathogen-Free and Conventional Rats
- Renal Tubulointerstitial Lesions in Mercuric Chloride-Treated Brown Norway Rats
- DORSAL SKIN LESIONS IN WBN/Kob-Ht RATS TOPICALLY TREATED WITH H_2O_2
- Lectinhistochemistry of Dorsal Skin of Wistar-derived Hypotrichotic WBN/Ila-Ht Rats
- Effects of Tacrolimus (FK506) on Encephalomyocarditic Virus-Induced Diabetes in Mice
- O-31 KINETICS OF MMPS AND THEIR REGULATORY FACTORS IN MERCURIC CHLORIDE-INDUCED TUBULOINTERSTITIAL LESIONS IN BROWN NORWAY RATS(Proceedings of the 27th Annual Meeting)
- Diurnal Changes in Intraepithelial Lymphocytes (IELs) in the Small Intestine of Mice
- "P-40 The Age-related Difference in Bone Changes in Rats induced by Recombinant Granulocyte Colony-Stimulating Factor
- Gene expression profiling in streptozotocin treated mouse liver using DNA microarray (TOXICOGENOMICS AND TOXICOPROTEOMICS) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
- Silver Selectivity of Novel Monoazapolythioether Derivatives Bearing a Hydrazone Group in the Solvent Extraction
- Highly Selective Copper(II) Extraction with Oligoethylene Glycol Bis(hydrazone)s as Several Compositional Complexes
- Determination of zearalenone and aflatoxins in maize(Others, Proceedings of the 32nd Annual Meeting)
- Contamination of Deoxynivalenol and T-2 toxin in rice(Others, Proceedings of the 32nd Annual Meeting)
- Pharmacokinetic Characteristics of Labeled-Nivalenoland -FusarenonX in Mice.(GENERAL SESSION BY POSTER PRESENTATION)(DRUG METABOLISM)
- Compositional Variation of Ionizable Crown Ether-Alkali Metal Ion Complexes in the Solvent Extraction Using Several Extraction Solvents
- T-2 Toxin-Induced Apoptosis and c-fos mRNA Expression in Con A-Stimulated Mouse Thymocyte Primary Cultures
- Picryl Chloride-Induced Contact Dermatitis in IQI/Jic Male Mice
- 5-Azacytidine-induced Apoptosis in Lymphoid and Hematopoietic Organs of Adult Mice
- Effects of Granulocyte Colony-Stimulating Factor on the Development of Inflammation in Bleomycin-Induced Lung Injury
- Morphological and Biochemical Changes During Aging and Photoaging of the Skin of C57BL/6J Mice
- Development of Apoptosis and Changes in Apoptosis-Related Genes Expression in the Thymus of Nivalenol-Treated Mice
- Early Ultrastructural Changes in the Dorsal Skin Epidermis of Wistar-Derived Hypotrichotic WBN/ILA-Ht Rats after UVB-Irradiation
- Renal Tubulointerstitial Lesions in Mercuric Chloride-Treated F344 Rats
- Comparison of Responses of Respiratory System to Cigarette Smoke Inhalation between Brown Norway and Fischer 344 Rats