鼻アレルギ-に対する2%Disodium Cromoglicate液剤の治療効果

概要

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To determine clinical effectiveness, clinical safety and convenience of administration, a 2% solution of Disodium Cromoglicate (DSCG) was prescribed for 30 patients with perennial nasal allergy. Responses to DSCG were measured by both subjective and objective parameters.Results: 1) The effectiveness was obtained in 73.4% of the patients and onset of the effect appeared within 2 weeks in more than 60% of cases. 2) The solution of DSCG was more effective in patients within one year than those with over a one year history of the disease. 3) The solution was also more effective in patients with Types I and II than those with Types III and IV by CMI test. 4) Subjectively, nasal obstruction showed the greatest improvement and objectively, watery secretion and swelling of the mucous membrane improved markedly. 5) The effectiveness and the safety of the solution were considered to be almost equal to those of the powder form. However, the solution was found to be superior to the powder form in convenience of use. 6) There were no side effects attributed to a 2% solution of DSCG.From these results, we summarize as follows: 1) A 2% solution of DSCG is effective in the treatment of perennial nasal allergy. 2) The solution is more easily applied than the powder form and is particularly useful for the treatment of young children.