Poliovirus resistant cells derived from HeLa cells.
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概要
- 論文の詳細を見る
A cell line from HeLa cells was established, which did not show a cytopathogenic effect (CPE) to poliovirus infection. The cell line, designated PRHC-1, did not regain susceptibility after more than 100 passages for one year. The poliovirus type 1-Mahoney, Sabin -2 and Sabin -3 also were not infective to PRHC -1 cells, however a bovine enterovirus (MZ-468) was. No binding activity of PRHC -1 cells to poliovirus Sabin -1 was observed. A chromosome analysis demonstrated no significant difference between PRHC -1 and its parental HeLa cells. Immunofluorescence staining demonstrated no persistent infection in PRHC -1 cells.
- 久留米大学医学部 The Kurume Medical Journal 編集部の論文
著者
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Nakamura Eiji
Department Of Electrical Engineering Faculty Of Engineering Kanagawa University
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Shingu Masahisa
Department Of Virology Kurume University School Of Medicine
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Xu Bing
Department Of Military Epidemiology College Of Military Prevention Third Military Medical University
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SHINGU MASAHISA
Department of Microbiology, Kurume University School of Medicin
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CHINAMI MASANOBU
Department of Virology Kurume University School of Medicine
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CHINAMI MASANOBU
Department of Gynecology and Obstetrics, Kurume University, School of Nedicine
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KAKISAKO SHINICHI
Department of Virology Kurume University School of Medicine
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KAKISAKO SHINICHI
Department of Internal Medicine, Kurume University School of Medicine
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SHINGU MASAHISA
Department o f Microbiology, Kurume University School of Medicine
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XU BING
Department of Virology Kurume University School of Medicine
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