Cerebrospinal fluid cytology using a cytocentrifuge in the early diagnosis of cause of meningitis.

概要

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A Cytocentrif uge was found to be an effective and rapid tool preparing cytological samples from cerebrospinal fluid for diagnosing bacterial, neoplastic and viral meningitis as well as herpes simplex encephalitis. Using the centrifuge, we have been able to make early diagnoses for various type of the disease and to give prompt treatments for patients. Some of our successful cases using the system were listed as follows: (1) After observing vacuolated phagocyte with coccus which was definitely bacterial meningitis, patients could be administered immediately antibiotics. (2) A patient of herpes simplex encephalitis whose phagocytes either with hemosiderin and erythrocytes or hemosiderin showed excellent result with adenosine arabinoside. (3) Tumor cells in the first tap from the lumbar of a patient of meningeal carcinomatosis were readily demonstrated with this system. (4) Only in the viral meningitis, lymphocytes with multilobulated nuclei which resembled abnormal adult T-cell leukemia cells and atypical lymphocytes were observed.
久留米大学医学部 The Kurume Medical Journal 編集部の論文