Tumor regression and growth rate of tumor after transcatheter arterial embolization for patients with hepatocellular carcinoma.

概要

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Eighty-five patients received transcatheter arterial embolization (TAE) for unresectable hepatocellular carcinoma (HCC). In fourty-four patients of them, tumor size was measured by ultrasonography, computed tomography or angiography befor and after TAE. In two patients with complete response (CR), tumors disappeared temporarily on computed tomogram and angiogram, respectively. Tumor regression of over 50% (partial response, PR) was obtained in 20 patients and 25 to 50% regression (minor response, MR) in 11 patients. The other 11 patients had tumor regression less than 25% or progressive disease. Periods of effectiveness were 13 to 31 months in CR patients, 2 to 22 months in PR patients, and 2 to 12 months in MR patients. Degree of tumor regression had a close relationship with the length of survival. The effect of tumor regression was the most remarkable in HCC of 3-4cm in diameter and very poor in HCC larger than 8cm in diameter. The growth rate of tumor after TAE correlated well with duration of survival and seemed usefull for prognostic estimation.
社団法人日本肝臓学会の論文