愛隣地区のアルコ-ル多飲慢性肝疾患患者におけるHB抗原・抗体系について--同地区慢性肝疾患の病因に関する検討

概要

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In this district, patients without hepatic diseases gave a positive rate for HBsAg of approximately 2%, which is not so much different from the average of the entire Japanese population.<BR>Patiemts with chromic liver diseases gave an exceedixxgly low value of 5% (11 out of 244) for positivity of HBsAg. However, the positive rate for anti-HB antibodies (anti-HB and anti-HBc) accounted for 67% of patients withont hepatic diseases and 68% of patients with chronic liver diseases.<BR>It seems that infection with hepatitis B virus in adults, in many instances, terminates in a mere immune response of antibody production without establishing a chronic liver disease associated with a positivity of HBsAg.<BR>Changes that conform to the histological crlteria of alcoholic liver damage were seen in many instances.<BR>It may be pointed out that most of the chronic liver disease in this district seems to be caused by heavy drink of alcohol.
社団法人日本肝臓学会の論文