An autopsy case of hepatocellular carcinoma survived for five years and eight months after embolization therapy.

概要

論文の詳細を見る
A 55-year-old man with chronic abuse of alcohol was admitted to our hospital because of abnormal liver scintigram. A selective hepatic angiogram disclosed a large hypervascular tumor and multiple daughter nodules in the right lobe. Because the tumor was considered unresectable because of liver cirrhosis gelfoam embolization of the right hepatic artery was performed. The 26 days after embolization revealed no tumor vascularity and AFP value decreased from 1006ng/ml to 26ng/ml on the 46th postoperative day. Four times of embolization produced right hepatic arterial obstruction, with resulting development of collateral pathway such as left hepatic artery and right inferior phrenic artery. Especially embolization of right inferior phrenic artery was so effective that AFP value dropped from 78800ng/ml to 17.1ng/ml. But the subsequent angiogram demonstrated tumor invasion to the right adrenal gland and right kidney. Patient died to cachexy 5 years and 8 months after the first embolization. Histological finding revealed well differentiated hepatocellular carcinoma, Edmondson's grade II.
社団法人日本肝臓学会の論文