DOPAMINE RECEPTOR IN ANTERIOR BYSSUS RETRACTOR MUSCLE OF MYTILUS EDULIS
スポンサーリンク
概要
- 論文の詳細を見る
Effects of dopamine, N-methyl-, ethyl and propyl-derivatives of dopamine, and alpha and beta-adrenoceptor stimulants on catch contraction of anterior byssus retractor muscle of Mytilus edulis were tested. The test drugs except the beta-adrenoceptor stimulants relaxed catch contraction. Dopamine was most active and substitution of amino group in dopamine with ethyl and propyl decreased activity considerably. The concentration-action curves of dopamine, its derivatives and norepinephrine shifted in parallel with application of haloperidol but were not influenced by the alpha and beta-adrenoceptor antagonists. These results suggest that relaxation of catch contraction by catecholamines is mediated through a dopamine receptor. This muscle is considered to be suitable for a study of the dopamine receptor.
- 社団法人 日本薬理学会の論文
著者
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TAKAYANAGI Issei
Department of Chemical Pharmacology, Toho University School of Pharmaceutical Sciences
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Takayanagi Issei
Department Of Chemical Pharmacology Toho University School Of Pharmaceutical Sciences
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Takayanagi Issei
Department Of Chemical Pharmacology Faculty Of Pharmaceutical Sciences University Of Tokyo:(correspo
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MURAKAMI Hajime
Department of Physiology and Anatomy, Nihon University College of Pharmacy
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Yoshida Yukiko
Department Of Chemical Pharmacology Toho University School Of Pharmaceutical Sciences
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IWAYAMA Yumiko
Department of Chemical Pharmacology, Toho University School of Pharmaceutical Sciences
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MIKI Saori
Department of Chemical Pharmacology, Toho University School of Pharmaceutical Sciences
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Iwayama Yumiko
Department Of Chemical Pharmacology Faculty Of Pharmaceutical Sciences The University Of Tokyo
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YOSHIDA YUKIKO
Department of Chemical Pharmacology, Toho University School of Pharmaceutical Sciences
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Murakami Hajime
Department of Imaging Devices Research, Hitachi, Ltd., Materials Research Laboratory, Hitachi, Ibaraki 319-1292, Japan
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