INHIBITORY ACTION OF 2-(1,2-BENZISOXAZOL-3-YL)-3-[2-(2-PIPERIDINOETHOXY)PHENYL]ACRYLONITRILE (SX-284) ON ACETYLCHOLINE RELEASE FROM VAGUS NERVE IN GUINEA PIG ILEUM
スポンサーリンク
概要
- 論文の詳細を見る
Newly synthesized compound, 2-(1-, 2-benzisoxazol-3-yl)-3-[2-(2-piperidinoethoxy)phenyl]acrylonitrile (SX-284) inhibited electrically evoked acetylcholine release from the stores in the myenteric plexus-longitudinal strips of guinea pig ileum which was labelled with [^3H]-choline but not the evoked release of tracer from rat vas deferens after labelling with [^3H]-norepinephrine. These results support our previous findings that SX-284 specifically inhibit acetylcholine release from the vagus nerve in the gastrointestinal canal.
- 公益社団法人日本薬学会の論文
著者
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Takayanagi Issei
Department Of Chemical Pharmacology Faculty Of Pharmaceutical Sciences University Of Tokyo:(correspo
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Sone Hideko
Department Of Chemical Pharmacology Toho University School Of Pharmaceutical Sciences
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