PHARMACOLOGICAL PROPERTIES OF CODEINE-7, 8-OXIDE (CODEINE EPOXIDE), A NEW METABOLITE OF CODEINE
スポンサーリンク
概要
著者
-
TAKAYANAGI Issei
Department of Chemical Pharmacology, Toho University School of Pharmaceutical Sciences
-
Miyata Naoki
Department of Organic & Medicinal Chemistry, Nagoya City University, Graduate School of Pharmaceutic
-
HIROBE Masaaki
Department of Bioorganic and Medicinal Chemistry
-
Takayanagi Issei
Department Of Chemical Pharmacology Faculty Of Pharmaceutical Sciences University Of Tokyo:(correspo
-
Konno Fukio
Department Of Chemical Pharmacology Toho University School Of Pharmaceutical Sciences
-
WATANABE Keizo
Department of Polymer Science and Engineering, Kyoto Institute of Technology
-
Miyata Naoki
Department Of Bioorganic And Medicinal Chemistry Faculty Of Pharmaceutical Sciences University Of To
-
Watanabe Keizo
Department Of Polymer Science And Engineering Kyoto Institute Of Technology
-
WATANABE Keizo
Department of Bioorganic and Medicinal Chemistry, Faculty of Pharmaceutical Sciences, University of Tokyo
-
KONNO FUKIO
Department of Biology, Faculty of Science, Kobe University
関連論文
- The Characteristics of Endothelin Receptor Subtypes on Muscle Contraction and Neuro-transmission in Rat Vas Deferens
- THE ACTIONS OF SODIUM NITROPRUSSIDE AND DILTIAZEM ON CALCIUM-, POTASSIUM- AND HISTAMINE-INDUCED CONTRACTILE RESPONSES IN ISOLATED RABBIT BASILAR ARTERY, AORTA, TAENIA COLI AND TRACHEAL SMOOTH MUSCLE
- Gene expression profiles of hepatotoxin-treated human hepatocytes can be used to cluster unknown compounds according to their mode of action(Toxicogenomics, Toxicoproteomics, Proceedings of the 32nd Annual Meeting)
- Structure-Activity Relationships of Phenylethylamine Analogs in Their Serotonergic Depressant Effects on the Spinal Monosynaptic Reflex in Rats
- Enhancement of Spinal Monosynaptic Reflexes with Phenylethylamine and Related Drugs through Descending Noradrenergic Neurons
- 3P-016 マウスプリオンタンパク質ミュータントの線維形成(蛋白質-構造,第47回日本生物物理学会年会)
- Nitration of Specific Tyrosine Residues of Cytochrome c Is Associated with Caspase-Cascade Inactivation(Biochemistry)
- EFFECTS OF NICOTINE IN THE ISOLATED AIRWAY SMOOTH MUSCLE PREPARATIONS
- PHARMACOLOGICAL CHARACTERIZATION OF IONOPHORE X537A-INDUCED CONTRACTILE RESPONSES IN ISOLATED RABBIT TAENIA COLI AND AORTA
- A POSSIBLE MECHANISM OF ACTION OF A BETA-ADRENERGIC PARTIAL AGONIST (CARTEOLOL) IN GUINEA PIG TAENIA CAECUM
- Characteristics of Ca^ Oscillations in Ileal Longitudinal Muscle Cells of Guinea Pig
- Differences of Antagonism for a Selective α_-Adrenoceptor Antagonist BMY 7378 in the Rabbit Thoracic Aorta and Iliac Artery
- The β_2- and β_3-Adrenoceptor-Mediated Relaxation Induced by Isoprenaline and Salbutamol in Guinea Pig Taenia Caecum
- Signal Transduction Pathway Involved in β_3 - Adrenoceptor - Mediated Relaxation in Guinea Pig Taenia Caecum
- GREATER TENSION IS DEVELOPED AT THE SAME LEVEL OF CYTOSOLIC Ca^ CONCENTRATION IN THE PRESENCE OF CLONIDINE, AN ADRENERGIC PARTIAL AGONIST, THAN IN THE PRESENCE OF NOREPINEPHRINE
- EFFECTS OF AGING ON ALPHA-1 AND-2 ADRENOCEPTOR MECHANISMS IN SMOOTH MUSCLES
- ALPHA_1-ADRENOCEPTOR MECHANISM AND AGING
- INTERACTIONS OF BEFUNOLOL, A BETA-ADRENERGIC PARTIAL AGONIST, AND ITS DERIVATIVES WITH HIGH AND LOW AFFINITY SITES IN BETA-ADRENOCEPTORS
- INTERACTION OF DYNORPHIN DERIVATIVE CONTAINING 3-NITRO-2-PYRIDINESULFENYL (Npys) GROUP WITH OPIOID RECEPTORS
- Effects of a New Positive Inotropic Agent with a Vasodilatory Action, 5-Methyl-6-(4-pyridyl)-2H-1,4-thiazin-3 (4H)-one (ZSY-27), on Calcium-Movement and Mechanical Response in Rabbit Thoracic Aorta
- EFFECTS OF SMOOTH MUSCLE STIMULANTS ON I-ISOPRENALINE-β-ADRENOCEPTOR INTERACTION IN TAENIA FROM GUINEA PIG CAECUM
- CHARACTERIZATION OF NOREPINEPHRINE-INDUCED CONTRACTILE RESPONSE IN ISOLATED RABBIT BASILAR ARTERY
- PHARMACOLOGICAL ACTIONS OF LEUKOTRIENES C_4,D_4 AND E_4 ON GUINEA PIG ISOLATED TAENIA CAECUM AS A PREPARATION TO STUDY LEUKOTRIENES
- THE ACTIONS OF D 600, ASPAMINOL AND PAPAVERINE ON CALCIUM-, POTASSIUM- AND HISTAMINE-INDUCED CONTRACTIONS OF ISOLATED RABBIT BASILAR ARTERY, AORTA, TAENIA COLI AND TRACHEAL SMOOTH MUSCLE
- Relationship between Cyclic Nucleotide Levels and 5-Methyl-6-(4-pyridyl)-2H-1,4-thiazin-3 (4H)-one (ZSY-27), a New Positive Inotropic Agent with a Vasodilatory Action, -Induced Relaxation of Rabbit Thoracic Aorta
- Effects of a New Positive Inotropic Agent with a Vasodilatory Action, 5-Methyl-6-(4-pyridyl)-2H-1,4-thiazin-3 (4H)-one (ZSY-27), on Agonists-Induced Contractions in the Isolated Rabbit Thoracic Aorta
- PHARMACOLOGICAL MULTIPLICITY OF RECEPTOR SITES FOR THE MAMMALIAN TACHYKININS IN RABBIT IRIS SPHINCTER MUSCLE
- EFFECTS OF A COMBINED STOMACHIC AND ITS INGREDIENTS ON RABBIT STOMACH MOTILITY IN SITU
- CALCIUM IONS AND RELAXATION OF INTESTINAL SMOOTH MUSCLE INDUCED BY PAPAVERINE AND ASPAMINOL
- DOPAMINE AND ITS ANTAGONISTS ON MOLLUSCAN SMOOTH MUSCLE
- DOPAMINE RECEPTOR IN ANTERIOR BYSSUS RETRACTOR MUSCLE OF MYTILUS EDULIS
- INHIBITORY ALPHA-ADRENERGIC ACTION OF PHENYLEPHRINE IN GUINEA PIG TAENIA CAECUM
- NONSPECIFIC INHIBITORY ACTION OF CHINOFORM ON GASTROINTESTINE
- INTERACTION OF MORPHINE-EPOXIDE WITH MULTIPLE OPIATE RECEPTORS
- INTERACTION OF MORPHINE AND CODEINE-EPOXIDES WITH OPIATE RECEPTOR
- SOME PHARMACOLOGICAL PROPERTIES OF MORPHINE-7,8-OXIDE (MORPHINE EPOXIDE)
- PHARMACOLOGICAL PROPERTIES OF CODEINE-7, 8-OXIDE (CODEINE EPOXIDE), A NEW METABOLITE OF CODEINE
- EFFECTS OF EPOXIDES OF HEROIN, MORPHINE AND CODEINE ON THE ELECTRICALLY STIMULATED GUINEA PIG ILEUM
- EFFECTS OF COCAINE ON Ca-MOBILITY IN MICROSOMAL FRACTION FROM RAT VAS DEFERENS
- EFFECTS OF ACETYLCHOLINE AND HISTAMINE ON MECHANICAL ACTIVITY OF RABBIT TAENIA COLI, Ca-INCORPORATION AND Ca-RELEASE IN ITS MICROSOMAL FRACTION
- NONSPECIFIC RELAXATION OF INTESTINAL SMOOTH MUSCLE INDUCED BY ANTISPASMODICS AND MOVEMENT OF CALCIUM IONS
- DRUG-INDUCED SMOOTH MUSCLE CONTRACTION WITH NO CHANGE IN THE LEVEL OF CYCLIC GMP
- INHIBITION OF Ca-MOVEMENT AND MECHANICAL MOVEMENT IN RABBIT TAENIA COLI BY A SMOOTH MUSCLE RELAXANT (SULOCTIDIL)
- EFFECTS OF SMOOTH MUSCLE RELAXANT (ASPAMINOL) ON Ca-UPTAKE BY MITOCHONDRIAL AND MICROSOMAL FRACTIONS FROM RAT UTERUS
- EFFECTS OF NONSPECIFIC SMOOTH MUSCLE RELAXANTS ON CALCIUM-UPTAKE BY MICROSOMAL FRACTION AND THEIR INHIBITORY ACTION IN RABBIT TAENIA COLI
- EFFECTS OF CALCIUM IONS AND MAGNESIUM IONS ON 5-HYDROXYTRYPTAMINE-RECEPTOR INTERACTION
- EFFECTS OF NONSPECIFIC SMOOTH MUSCLE RELAXANTS ON GLYCOGEN PHOSPHORYLASE ACTIVITY IN DEPOLARIZED TAENIA CAECUM OF GUINEA PIG
- EFFECTS OF NONSPECIFIC SMOOTH MUSCLE RELAXANTS ON TISSUE CONCENTRATIONS OF HIGH ENERGY PHOSPHATES AND MECHANICAL ACTIVITY OF NORMAL POLARIZED AND DEPOLARIZED INTESTINAL SMOOTH MUSCLES FROM GUINEA PIG
- ANTIPHOSPHODIESTERASE ACTIVITY AND NONSPECIFIC SMOOTH MUSCLE RELAXATION TESTED ON INTESTINAL SMOOTH MUSCLES
- EXTERNAL CALCIUM IONS AND MECHANICAL RESPONSES OF THE AORTA ISOLATED FROM THE CHOLESTEROL-FED RABBIT
- RELAXING ACTION OF SYNTHETIC ANTISPASMODICS ON THE INTESTINAL SMOOTH MUSCLE OF GUINEA PIG
- INTRACELLULAR CYCLIC ADENOSINE 3, 5-MONOPHOSPHATE AND RELAXING EFFECTS OF ISOPRENALINE AND PAPAVERINE ON SMOOTH MUSCLE OF INTESTINE
- POSSIBLE MECHANISMS OF STIMULATORY ACTION OF PAPAVERINE ON CALCIUM-UPTAKE BY RAT UTERINE MICROSOMAL FRACTION
- EFFECTS OF ANTI-ASTHMATIC DRUGS ON AIRWAY RESISTANCE AND PLASMA LEVEL OF CYCLIC AMP IN GUINEA PIG
- RELATIONSHIP BETWEEN THE Ba-INDUCED CONTRACTION AND CYCLIC AMP LEVELS IN THE ISOLATED LONGITUDINAL SMOOTH MUSCLE FROM GUINEA PIG ILEUM
- A DUAL ACTION OF MUSCARINIC PARTIAL AGONISTS ON PUPIL SIZE OF RABBIT
- A DIFFERENCE IN PHARMACOLOGICAL PROPERTIES OF HISTAMINE RECEPTORS IN RABBIT AORTA AND BASILAR ARTERY
- EFFECTS OF NONSPECIFIC SMOOTH MUSCLE RELAXANTS AND Ca-BLOCKER ON Ca-RELEASE AND Ca-BINDING IN MICROSOMAL FRACTIONS FROM RABBIT TAENIA COLI
- ACTIONS OF PAPAVERINE, ASPAMINOL AND BILE SALTS AND INTRACELLULAR CYCLIC AMP LEVEL
- COMPARISON OF ACTIONS OF PAPAVERINE, ASPAMINOL AND ISOPRENALINE ON ISOLATED RAT UTERUS
- ANTI-OXYTOCIN ACTIONS OF PAPAVERINE, ASPAMINOL AND ISOPRENALINE ON THE RAT UTERUS AND INTRACELLULAR CYCLIC ADENOSINE 3, 5-MONOPHOSPHATE LEVEL
- INHIBITORY ACTION OF 2-(1,2-BENZISOXAZOL-3-YL)-3-[2-(2-PIPERIDINOETHOXY)PHENYL]ACRYLONITRILE (SX-284) ON ACETYLCHOLINE RELEASE FROM VAGUS NERVE IN GUINEA PIG ILEUM
- RELATIONSHIP BETWEEN SYNAPTOSOMAL CALCIUM UPTAKE AND ANTINOCICEPTIVE ACTION OF MORPHINE
- EFFECT OF 1, 1-DIPHENYL-3-PIPERIDINOBUTANOL HYDROCHLORIDE (ASPAMINOL) ON THE STIMULI-INDUCED CALCIUM UPTAKE IN RAT BRAIN SYNAPTOSOMES
- EFFECTS OF MORPHINE, CODEINE AND CODEINE-EPOXIDE ON CALCIUM UPTAKE INTO THE SYNAPTOSOMES ISOLATED FROM NAIVE AND TOLERANT RATS
- EFFECT OF MORPHINE ON THE STIMULI-INDUCED CALCIUM UPTAKE INTO SYNAPTOSOMES ISOLATED FROM MORPHINE-TOLERANT RATS
- SPECIFIC 3H-HALOPERIDOL BINDING TO DOPAMINE RECEPTORS IN THE ANTERIOR BYSSUS RETRACTOR MUSCLE OF MYTILUS EDULIS
- EFFECTS OF SOME ERGOT ALKALOIDS ON DOPAMINE RECEPTORS OF MOLLUSCAN SMOOTH MUSCLE
- MEAHANISM OF ACTION OF NICOTINE IN ISOLATED URINARY BLADDER FROM GUINEA-PIG
- ACTIONS OF DIBUTYRYL CYCLIC ADENOSINE MONO-PHOSPHATE, PAPAVERINE AND ISOPRENALINE ON THE INTESTINAL SMOOTH MUSCLE
- ACTION OF DIBUTYRYL CYCLIC ADENOSINE MONOPHOSPHATE ON THE INTESTINAL SMOOTH MUSCLE
- EFFECT OF N6, 2-O-DIBUTYRYL 35-CYCLIC ADENOSINE MONOPHOSPHATE, 3, 5, -CYCLIC ADENOSINE MONOPHOSPHATE AND ADENOSINE TRIPHOSPHATE ON ACETYLCHOLINE OUTPUT FROM CHOLINERGIC NERVES IN GUINEA PIG ILEUM
- EFFECTS OF A REDUCTION IN EXTERNAL SODIUM ION CONCENTRATION ON ACTIONS OF SOME SMOOTH MUSCLE STIMULANTS
- BETA-ADRENOCEPTORS IN THE GUINEA PIG TREATED WITH EGG-ALBUMIN
- THE EFFECTS OF CAFFEINE AND IMIDAZOLE ON THE ACTIONS OF BETA- AND ALPHA-ADRENERGIC STIMULANTS, PAPAVERINE AND CYCLIC 3, 5-AMP
- POSSIBLE MECHANISMS OF A NEW TYPE OF ANTISPASMODIC DRUG, BTM-1042(CIS-(-)-2, 3-DIHYDRO-3-(4-METHYL-PIPERAZINYL)METHYL-2-PHENYL-1, 5-BENZOTHIAZEPIN-4(5H)-ONE DIHYDROCHLORIDE)
- A NEW PARASYMPATHOMIMETIC AGENT: 1-METHYL-5-CHLOROINDOLINE METHYLBROMIDE
- A RECEPTOR RESERVE OF THE ALPHA-INHIBITORY RECEPTOR FOR ALPHA-ADRENOCEPTOR STIMULANTS IN THE TAENIA CAECUM OF GUINEA PIG
- ACTIVATION OF GUANYLATE CYCLASE AS SECONDARY REACTION FOLLOWING INCREASE IN INTRACELLULAR Ca ION CONCENTRATIONS
- RELATIONSHIP BETWEEN INTRINSIC ACTIVITY OF β-ADRENOCEPTOR AGONIST AND AMOUNT OF SPARE RECEPTORS IN GUINEA PIG TAENIA CAECUM
- A POSSIBLE MECHANISM OF A NEW ANTISPASMODIC DRUG, 2-(1, 2-BENZISOXAZOL-3-YL)-3-[2-(2-PI PER IDINOETHOXY) PHENYL]ACRYLONITRILE (SX-284)
- PHARMACOLOGICAL PROPERTIES OF ACETYLCHOLINE RECEPTOR IN MOLLUSCAN SMOOTH MUSCLE
- THE ACTION OF DIBUTYRYL CYCLIC GMP (N2-2 O-DIBUTYRYL CYCLIC GUANOSINE-3, 5-MONO-PHOSPHATE) ON THE ILEUM OF GUINEA PIG
- EFFECT OF ACETYLCHOLINE ON DESENSITIZATION OF ISOLATED RAT TRACHEA TO 5-HYDROXYTRYPTAMINE —A POSSIBLE ALLOSTERIC INTERACTION BETWEEN DRUG RECEPTORS
- INTERACTIONS OF SOME PARTIAL AGONISTS WITH BETAADRENOCEPTOR IN GUINEA-PIG TAENIA CAECUM
- CALCIUM-INDUCED STIMULATION OF 45-CALCIUM-EFFLUX IN SMOOTH MUSCLE MICROSOMES
- EFFECTS OF ACETYLCHOLINE RELEASING DRUGS ON ELECTRICAL ACTIVITIES OBTAINED FROM AUERBACHS PLEXUS IN THE GUINEA PIG ILEUM
- PHARMACOLOGICAL PROPERTIES OF ELECTRICAL ACTIVITIES OBTAINED FROM NEURONS IN AUERBACHS PLEXUS
- BETA-ADRENERGIC BLOCKING ACTION OF RUTHENIUM RED
- MECHANISM OF ACTION OF RYANODINE AND REQUIREMENT OF OPERATION OF Ca-INDUCED Ca RELEASE FOR ONSET OF THE DRUG'S ACTION IN MAMMALIAN SMOOTH MUSCLE
- EFFECTS OF PHENOBARBITAL ON PLASMA CONCENTRATION OF PHENYTOIN AND MORTALITY OF MICE TREATED WITH PHENYTOIN AFTER ELECTROSHOCK
- Effects of Morphine, Clonidine and Papaverine on Synaptosomal 45Ca Uptake and Antinociceptive Action in Rats
- PHYSIOLOGICAL CALCIUM ION CONCENTRATION AND A CHOLINERGIC DRUG ON ACTIVITY OF PARTICULATE GUANYLATE CYCLASE IN GUINEA PIG TAENIA CAECUM
- A POSSIBLE MECHANISM FOR THE OCCURRENCE OF THE NON-SPECIFIC POTENTIATION IN THE DENERVATED SKELETAL MUSCLE OF THE RAT
- EFFECTS OF SOME DIVALENT CATIONS ON THE DENERVATED SKELETAL MUSCLE OF THE RAT
- A DIFFERENCE IN PHARMACOLOGICAL ACTION OF R (+) AND S (-) ISOMERS OF BEFUNOLOL, BETA-ADRENOCEPTOR BLOCKER
- INTERACTION OF THE PARTIAL AGONISTS WITH BETA-ADRENOCEPTOR IN GUINEA-PIG TAENIA CAECUM
- BETA-ADRENOCEPTOR MECHANISMS IN GUINEA PIG TAENIA CAECUM
- RELATIONSHIP BETWEEN THE LEVELS OF INTRACELLULAR CYCLIC NUCLEOTIDES AND MECHANICAL RESPONSES INDUCED BY DRUGS
- Pharmacological Characterization of Contractile Responses Induced by .ALPHA.1-Agonists, Norepinephrine and Clonidine, by Selective Antagonists of Their Subtypes in Rabbit Thoracic Aorta.