SOME PHARMACOLOGICAL PROPERTIES OF MORPHINE-7,8-OXIDE (MORPHINE EPOXIDE)
スポンサーリンク
概要
- 論文の詳細を見る
Morphine-7,8-oxide (morphine epoxide) is assumed to be a metabolite of morphine. Morphine epoxide in antinociceptive action was practically as potent as morphine. The development of tolerance in antinociceptive action was slower in the rats treated with morphine epoxide than in the rats with morphine. Furthermore, morphine epoxide was less potent than morphine in the inhibition of abstinence syndrome.
- 公益社団法人日本薬学会の論文
著者
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TAKAYANAGI Issei
Department of Chemical Pharmacology, Toho University School of Pharmaceutical Sciences
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Miyata Naoki
Department of Organic & Medicinal Chemistry, Nagoya City University, Graduate School of Pharmaceutic
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HIROBE Masaaki
Department of Bioorganic and Medicinal Chemistry
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Takayanagi Issei
Department Of Chemical Pharmacology Faculty Of Pharmaceutical Sciences University Of Tokyo:(correspo
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Hirobe Masaaki
Department Of Bioorganic And Medicinal Chemistry Faculty Of Pharmaceutical Sciences University Of To
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Konno Fukio
Department Of Chemical Pharmacology Toho University School Of Pharmaceutical Sciences
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Konno F
Pharmaceutical Research Center Meiji Seika Kaisha
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SHIBATA REIKO
Department of Chemical Pharmacology, Toho University School of Pharmaceutical Sciences
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Shibata Reiko
Department Of Chemical Pharmacology Toho University School Of Pharmaceutical Sciences
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Shibata Reiko
Department Of Bioscience And Biotechnology Faculty Of Science And Engineering Ritsumeikan University
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Miyata Naoki
Department Of Bioorganic And Medicinal Chemistry Faculty Of Pharmaceutical Sciences University Of To
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KONNO FUKIO
Department of Biology, Faculty of Science, Kobe University
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