EFFECTS OF SOME ERGOT ALKALOIDS ON DOPAMINE RECEPTORS OF MOLLUSCAN SMOOTH MUSCLE
スポンサーリンク
概要
- 論文の詳細を見る
Some ergot alkaloids relaxed catch contraction of an isolated molluscan smooth muscle (anterior byssus retractor muscle of Mytilus edulis). Haloperidol, a competitive dopamine antagonist, shifted the dose response curves of ergot alkaloids, but methysergide did not. Bromoaiptine, a potent doparminergic ergot alkaloid, did not relax catch contraction. These results suggest that relaxation of catch contraction by some ergot alkaloids is mediated through dopamine receptors of this muscle, but dopamine receptors of this muscle seem to be somewhat different from those of mammalian brain.
- 公益社団法人日本薬学会の論文
著者
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Takayanagi Issei
Department Of Chemical Pharmacology Faculty Of Pharmaceutical Sciences University Of Tokyo:(correspo
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Ishii Yumiko
Department Of Chemical Pharmacology Toho University School Of Pharmaceutical Sciences
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Ishii Yumiko
Department of Biotechnology and Therapeutics, Graduate School of Pharmaceutical Sciences, Osaka University
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