EFFECTS OF ACETYLCHOLINE RELEASING DRUGS ON ELECTRICAL ACTIVITIES OBTAINED FROM AUERBACHS PLEXUS IN THE GUINEA PIG ILEUM
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概要
- 論文の詳細を見る
Effects of 5-hydroxytryptamine, sodium picrate, caerulein and pentagastrin on the electrical activities obtained from Auerbachs plexus in the guinea pig ileum were investigated. The drugs used increased the spike frequency and increase of the spike frequency induced was inhibited by morphine but not by atropine and hexamethonium. The muscle spikes obtained simultaneously were inhibited by atropine. These facts indicate that the drugs used stimulate Auerbachs plexus and accelerate the acetylcholine release from the cholinergic post-ganglinoic nerve endings. The sites of action of morphine are also discussed.
- 社団法人 日本薬理学会の論文
著者
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SATO Takao
Department of Physics,Faculty of Science,Tokyo Metropolitan University
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Takayanagi Issei
Department Of Chemical Pharmacology Faculty Of Pharmaceutical Sciences University Of Tokyo:(correspo
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TAKAGI Keijiro
Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, University of Tokyo
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Sato Takao
Department Of Biological Science And Technology Faculty Of Engineering The University Of Tokushima
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TAKAGI Keijiro
Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences University of Tokyo
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