Forskolin preferentially dilates the afferent arteriole in the canine kidney.
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概要
- 論文の詳細を見る
Intrarenal infusion of forskolin (0.2, μg/kg/min) in anesthetized dogs increased renal blood flow (RBF) and glomerular filtration rate (GFR) to the same degree but did not change the mean arterial pressure or heart rate. Forskolin also increased urine flow and urinary sodium excretion. The proportional increases in RBF and GFR may result from a preferential action of forskolin to dilate the afferent arteriole.
- 公益社団法人 日本薬理学会の論文
著者
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Tamaki Toshiaki
Department Of Pharmacology Kagawa Medical School
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Abe Youichi
Department Of Pharmacology Kagawa Medical University
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Kiyomoto Hideyasu
Department Of Cardio Renal And Cerebrovascular Medicine Kagawa University Faculty Of Medicine
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HASUI Kouichi
Departments of Kagawa Medical School Neurological Surgery Pharmacology
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Shoji Tetsuo
Department Of Metabolism Endocrinology And Molecular Medicine Graduate School Of Medicine
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Iwao Hiroshi
Department Of Cardiovascular Medicine Akita University Graduate School Of Medicine
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ABE Youichi
Department of Pharmacology, Kagawa Medical School
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AKI Yasuharu
Department of Pharmacology, Kagawa Medical School
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HASUI Kouichi
Department of Pharmacology, Kagawa Medical School
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