ニワトリ腎臓Ornithine Transcarbamylaseの誘導-2-卵黄中の粗蛋白質成分がOTC活性に及ぼす影響〔英文〕

概要

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Absorption of yolk accounts for an increase in ornithine transcarbamylase [EC 2. 1. 3. 3] (OTC) activity during development of chick embryos possessing Ob c gene. The preceding study showed that high fat content in the diet, but not any special component of the fat fraction of yolk, has an inducing effect on OTC activity. The present study was carried out to find if the non-fat fraction of yolk has any effect on OTC induction. Although non-fat yolk has no effects on OTC induction, an increased amount of it in the diet causes an increase in kidney weight. Thus net OTC activity on a whole kidney basis increases with an increase of the non-fat yolk content in diet. In combination with high fat content, replacement of non-fat yolk by amino acids mixtures was effective in OTC induction in a similar way to non-fat yolk. From these studies, it is suggested that non-fat yolk has no special protein components that induce OTC, but its high content of fat and protein causes the increase in OTC activity on a whole kidney basis: the former component increases the specific activity of OTC in the kidneys, and the latter increases the kidney weight.
社団法人日本畜産学会の論文