めん羊に比較的多量の硝酸塩を分与したときの血液中のメトヘモグロビン形成

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Four adult Japanese Corriedale wethers, about 50kg in body weight, were used in 4×4 factorial design trial. They were fed 600g of chopped timothy hay twice daily. Nitrate was administered immediately after the ingestion of the morning feeding via stomach tube into the rumen every seven days. A total of 22.5g of potassium nitrate was administered in each lots. Whole amount of nitrate was fed at 7:30a.m. at the treatment lot D, and at the treatment lots A, B and C, it was divided into two portions and fed at 7:30a.m. and 9:30 a.m. after animals ingested 300g of hay. Division of nitrate at each treatment lots were set as follows; Treatment A, 11.25g and 11.25g; Treatment B, 15.0g and 7.5g; Treatment C, 7.5g and 15.0g. Methemoglobin formation in blood was determined periodically after the first administration of nitrate into rumen. Results of analysis of variance showed a significant difference between treatments and between animals, but there was not significant difference between the experimental periods. Administration of potassium nitrate as much as 0.045% of body weight resulted in the conversion of at least 20% of hemoglobin to methemoglobin. On the other hand, when the same amount of nitrate was divided into two portions and administered at two hours interval, methemoglobin formation was apparently reduced. Therefore, it seems that when the amount of nitrate given at one time was small, the formation of methemoglobin may be reduced due to the rapid metabolism of nitrate in rumen. This may be one of the reasons why animals grazing slowly are not poisoned by consuming young plants containing much nitrate in early spring.
社団法人日本畜産学会の論文

めん羊に比較的多量の硝酸塩を分与したときの血液中のメトヘモグロビン形成

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