Lifespan Extending Activity of Substances Secreted by the Nematode Caenorhabditis elegans That Include the Dauer-Inducing Pheromone

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概要

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• The nematode Caenorhabditis elegans yields a substance(s) inducing the larval diapause, called dauer-inducing pheromone. We discovered that the crude pheromone extract extends the adult lifespan in the animal. This extension does not occur in the mutant animal, in which expansion of the lifespan caused by other mutations reducing insulin signaling is suppressed. This is the first description concerning the relevancy of the pheromone to the longevity in the animal.

• 2005-12-23

著者

• Kimura Y

  Department Of Bioresource Science Faculty Of Agriculture Tottori University

• KIMURA Yasuo

  Department of Agricultural Chemistry, Faculty of Agriculture, Tottori University

• Kimura Y

  Department Of Biological And Environmental Chemistry Faculty Of Agriculture Tottori University

• KAWANO Tsuyoshi

  Department of Biological and Environmental Chemistry, Faculty of Agriculture, Tottori University

• HONDA Yoko

  Tokyo Metropolitan Institute of Gerontology

• HONDA Shuji

  Tokyo Metropolitan Institute of Gerontology

• Kimura Yasuo

  Department Of Biological And Environmental Chemistry Tottori University

• KATAOKA Naoya

  Department of Biological and Environmental Chemistry, Tottori University

• ABE Sunao

  Department of Biological and Environmental Chemistry, Faculty of Agriculture, Tottori University

• OHTANI Mari

  Department of Biological and Environmental Chemistry, Faculty of Agriculture, Tottori University

• Abe Sunao

  Department Of Biological And Environmental Chemistry Faculty Of Agriculture Tottori University

• Ohtani Mari

  Department Of Biological And Environmental Chemistry Faculty Of Agriculture Tottori University

• Kataoka Naoya

  Department Of Biological And Environmental Chemistry Tottori University

• Honda Yoko

  東京都老人総合研究所 健康長寿ゲノム探索研究

• Kawano Tsuyoshi

  Department Of Bioresource Sciences Faculty Of Agriculture Tottori University

• Kawano Tsuyoshi

  Department Of Biological And Environmental Chemistry Faculty Of Agriculture Tottori University

• Kawano Tsuyoshi

  Dep. Of Bioresource Sciences Fac. Of Agriculture Tottori Univ.

• Kawano Tsuyoshi

  Department Of Biological And Environmental Chemistry Tottori University

• Kimura Yasuo

  Department Of Agricultural Chemistry Faculty Of Agriculture Tottori University

• Kimura Y

  Department Of Biological And Environmental Chemistry Tottori University

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