Beyerane Derivatives and a Sesquiterpene Dimer from Japanese Cypress : Chamaecyparis obtusa
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概要
- 論文の詳細を見る
In the course of studies on biological active constituents from woody plants, we previously reported the isolation of many lignan derivatives as neurite outgrowth-promoting compounds from an ethyl acetate soluble fraction of Japanese Cypress (Chamaecyparis obtusa). Further chemical investigation on the residual parts of the ethyl acetate soluble fraction of a methanol extract of Japanese Cypress resulted in the isolation of four new beyerene type derivatives and a novel sesquiterpene dimer formed between cryptomeridiol and hinokiic acid. Their structures were elucidated as 18-O-(Z)-p-coumaroylbeyer-15-ene-18-ol (1), 18-O-(E)-p-coumaroylbeyer-15-ene-18-ol (2), 18-O-(E)-p-coumaroylbeyer-15-ene-11β,18-diol (3), 18-O-(Z)-p-coumaroylbeyer-15-ene-11β,18-diol (4) and ent-cryptomeridiol-4-yl-hinokiiate (5) by ^1H-NMR, ^<13>C-NMR, 2D-NMR, and HR-MS spectral analysis.
- 社団法人日本薬学会の論文
- 2008-07-01
著者
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Wu Lijun
中華人民共和国
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Fuchino Hiroyuki
Research Center for Medicinal Plant Resources, National Institute of Biomedical Innovation
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Wu Li
School Of Traditional Chinese Materia Medica Shenyang Pharmaceutical University
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NAKANE Takahisa
Showa Pharmaceutical University
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SHIROTA Osamu
Faculty of Pharmaceutical Sciences, Kagawa Campus, Tokushima Bunri University
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KUROYANAGI Masanori
Faculty of Life and Enviromental Sciences, Prefectural University of Hiroshima
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Gao H
School Of Traditional Chinese Medicines Shenyang Pharaceutical University
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Gao Hui
School Of Traditional Chinese Medicines Shenyang Pharmaceutical University
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Kuroyanagi M
Fac. Of Pharmaceutical Sciences At Kagawa Campus Tokushima Bunri Univ.
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Shirota Osamu
Faculty Of Pharmaceutical Sciences At Kagawa Campus Tokushima Bunri University
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Shirota Osamu
Shiseido Research Center
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Muto Norio
Faculty Of Life And Environmental Sciences Prefectural University Of Hiroshima
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Wu Li
School Of Traditional Chinese Medicines Shenyang Pharmaceutical University
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SANO Toshikazu
Hiroshima Prefectural Forestry Research Center
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Fuchino H
Sci. Univ. Tokyo Tokyo Jpn
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Fuchino Hiroyuki
Research Center For Medicinal Plant Resources National Institute Of Biomedical Innovation
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Wang Li-bo
Kyoto Pharmaceutical University:faculty Of Natural Medicines Shenyang Pharmaceutical University
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Nakane Takahisa
Biological Sci. Res. Lab. Lion Corp.
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Nakane Takahisa
Showa Pharmaceutical Univ.
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Fuchino Hiroyuki
Res. Center For Medicinal Plant Resources National Inst. Of Biomedical Innovation
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Muto Norio
Faculty Of Life And Environmental Science Prefectural University Of Hiroshima
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Kuroyanagi Masanori
Fac. Of Pharmaceutical Sciences At Kagawa Campus Tokushima Bunri Univ.
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Kuroyanagi Masanori
Faculty Of Food Culture Department Of Nutrition Kurashiki Sakuyo University
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Kimura Mariko
Fac. Of Food Culture Dep. Of Nutrition Kurashiki Sakuyo Univ.
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Ohta Sanae
Laboratory Of Pharmacognosy And Natural Product Chemistry Faculty Of Pharmaceutical Sciences At Kaga
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Fuchino H
Research Center For Medicinal Plant Resources National Institute Of Biomedical Innovation
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Shirota Osamu
Faculty of Pharmaceutical Sciemces at Kagawa Campus, Tokushima Bunri Universiyty
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Nakane Takahisa
Showa Parmaceutical University
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GAO Hui
School of Information and Communication Engineering, Beijing University of Posts and Telecommunications
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