Echocardiographic Epicardial Fat Thickness and Coronary Artery Disease
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概要
- 論文の詳細を見る
Background The association between epicardial fat and coronary artery disease has not been evaluated. The objective of the present study was to evaluate the relationship of echocardiographic epicardial fat to the presence and severity of coronary artery disease in a clinical setting. Methods and Results Two hundred and three consecutive patients who underwent echocardiography and diagnostic coronary angiography were studied. The epicardial fat thickness on the free wall of the right ventricle was measured at end-diastole from the parasternal long-axis views of 3 cardiac cycles. Coronary angiograms were analyzed for the extent and severity of coronary artery disease using Gensini's score. The patients were divided into 2 groups according to the fourth quartile of epicardial fat thickness (Group I <7.6mm; Group II >7.6mm). There were no significant differences in the baseline characteristics except for waist circumference (p=0.023). Significant correlations were demonstrated between epicardial fat thickness and age (r=0.332, p<0.001), C-reactive protein (r=0.182, p=0.009), body mass index (r=0.142, p=0.044) and waist circumference (r=0.229, p=0.001). The patients with a higher epicardial fat thickness were associated with a high Gensini's score (p=0.014). Multivariate analysis showed that age (odds ratio (OR) 5.29, p=0.003), epicardial fat thickness (OR 10.53, p=0.004), diabetes (OR 8.06, p=0.006) and smoking (OR 14.65, p=0.015) were independent factors affecting significant coronary artery stenosis. Conclusions Epicardial fat thickness was significantly correlated with the severity of coronary artery disease in patients with known coronary artery disease.
- 社団法人日本循環器学会の論文
- 2007-03-20
著者
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LEE Eun
Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of
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JEONG Myung
The Heart Center of Chonnam National University Hospital
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PARK Jong
The Heart Center of Chonnam National University Hospital
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LEE Je
Department of Hematology, Chonnam University Hwasun Hospital
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Jeong Myung
Chonnam National University Hospital
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Park Eun
Department Of Biochemistry Kon Kuk University
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Park Eun
Wonkwang University Hospital
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Kim Yun
Departments Of Cardiovascular Medicine Wonkwang University Hospital
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Jeong Myung
Yonsei University Wonju Hospital
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Oh Seouk
Gachon University Gil Medical Center
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Oh Seok
Heart Center of Chonnam National University Hospital
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Kim Nam-ho
Wonkwang University Hospital
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Jeong Jin-won
Wonkwang University Hospital
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Oh Seok
Wonkwang University Hospital
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Park Jong
Chonnam National University Hospital
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Oh Seok
Department of Cardiology, Wonkwang University Hospital
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YOO Nam
Department of Pathology, College of Medicine, Catholic University of Korea
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Kim Nam
Departments Of Cardiovascular Medicine Wonkwang University Hospital
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Park Eun
Department Of Anatomy And Cell Biology College Of Veterinary Medicine And School Of Agricultural Bio
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Yun Kyeong
Departments of Cardiovascular Medicine, Wonkwang University Hospital
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Rhee Sang
Departments of Cardiovascular Medicine, Wonkwang University Hospital
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Jeong Jin-Won
Departments of Cardiovascular Medicine, Wonkwang University Hospital
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Kirn Yun
Departments of Cardiovascular Medicine, Wonkwang University Hospital
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Kirn Nam-Ho
Departments of Cardiovascular Medicine, Wonkwang University Hospital
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Jeong Jin-won
Departments Of Cardiovascular Medicine Wonkwang University Hospital
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Rhee Sang
Departments Of Cardiovascular Medicine Wonkwang University Hospital
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Lee Eun
Wonkwang University Hospital
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Yoo Nam
Wonkwang University Hospital
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Yoo Nam
Department Of Pathology College Of Medicine Catholic University Of Korea
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Yun Kyeong
Wonkwang University Hospital
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Kim Nam-ho
Departments Of Cardiovascular Medicine Wonkwang University Hospital
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Rhee Sang
Department Of Endocrinology And Metabolism Kyung Hee University School Of Medicine
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Jeong Myung
Department Of Cardiovascular Medicine Chonnam National University Medical School
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Lee Eun
Department Of Anesthesiology And Pain Medicine Asan Medical Center University Of Ulsan College Of Me
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Rhee Sang
Department of Cardiovascular Medicine, Regional Cardiocerebrovascular Center, Wonkwang University Hospital
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Yun Kyeong
Department of Cardiovascular Medicine, Regional Cardiocerebrovascular Center, Wonkwang University Hospital
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Yoo Nam
Department of Cardiovascular Medicine, Wonkwang University Hospital
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Jeong Jin-Won
Department of Cardiovascular Medicine, Wonkwang University Hospital
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Jeong Jin-Won
Department of Cardiovascular Medicine, Regional Cardiocerebrovascular Center, Wonkwang University Hospital
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