Periodic Variation and Its Effect on Management and Prognosis of Korean Patients With Acute Myocardial Infarction
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概要
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Background: The characteristics of the periodic variation in acute myocardial infarction (AMI) and the subsequent effect on management and prognosis have not been fully investigated in a large number of Asian populations. Methods and Results: From a prospective, observational multicenter online registry, 4,573 patients diagnosed as AMI in Korea from January to December 2006 were included. The highest incidence of AMI was between 8 a.m. and noon. The number of cases was highest in the winter and lowest in the autumn (13.6 vs 11.4 patients per day, P<0.001). Patients with symptom onset during working hours had a shorter time to first medical contact (203±288 min) compared with out-of-hours onset (230±288 min, P=0.003). In patients who underwent primary angioplasty, out-of hours symptom onset was associated with a greater time delay in both the patients and the medical facilitys response (door-to-balloon time out-of hours vs working hours: 101±54 min vs 84±44 min, P<0.001). In patients with ST-segment elevation myocardial infarction, symptoms to first medical contact showed a significant relationship to in-hospital mortality (for every 10 min of symptoms to first medical contact, odds ratio 1.006, 95% confidence interval 1.001-1.012, P=0.018) Conclusions: Circadian and periodic variation in AMI exists in Korean patients, which resulted in different patient behavior, hospital management and outcomes.
- 2010-04-25
著者
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Ahn Young
The Heart Center Of Chonnam National University Hospital
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Koo Bon-Kwon
Cardiovascular Center, Seoul National University Hospital
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Park Hyo
Division of Cardiology, Department of Internal Medicine, College of Medicine, Seoul National Univers
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Koo Bon-Kwon
Division of Cardiology, Department of Internal Medicine, College of Medicine, Seoul National Univers
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Lee Wonjae
Division of Cardiology, Department of Internal Medicine, College of Medicine, Seoul National Univers
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Cho Youngjin
Division of Cardiology, Department of Internal Medicine, College of Medicine, Seoul National Univers
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Park Jin
Department of Internal Medicine, Sejong General Hospital
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Choi Ji-Yong
Division of Cardiology, Department of Internal Medicine, College of Medicine, Daegu Catholic Univers
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Jeong Myung-Ho
Division of Cardiology, Department of Internal Medicine, College of Medicine, Chonnam National Unive
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Kim Jong
Busan Hanseo Hospital
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Chae Shung
Division of Cardiology, Kyungpook National University Hospital
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Kim Young
Division of Cardiology, Yeungnam University Medical Center
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Nam Chang-Wook
Division of Cardiology, Keimyung University Dongsan Medical Center
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Lee Jae-Hwan
Division of Cardiology, Chungnam National University Hospital
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Choi Dong
Division of Cardiology, Yonsei University Severans Hospital
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Hong Taek
Division of Cardiology, Pusan National University Hospital
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Chae Jei
Division of Cardiology, Chonbuk National University Hospital
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Rhew Jae
Jeonju Presbyterian Medical Center
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Kim Kee
Division of Cardiology, Department of Internal Medicine, College of Medicine, Daegu Catholic Univers
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Kim Hyo-Soo
Division of Cardiology, Department of Internal Medicine, College of Medicine, Seoul National Univers
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Oh Byung-Hee
Division of Cardiology, Department of Internal Medicine, College of Medicine, Seoul National Univers
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Park Young
Division of Cardiology, Department of Internal Medicine, College of Medicine, Seoul National Univers
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Koo Bon-kwon
Seoul National University Hospital
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Koo Bon
Heart Center Of Chonnam National University Hospital
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Park Kyung
Department Of Laboratory Medicine Seoul National University College Of Medicine:seoul National Unive
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Park Kyung-woo
韓国
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Kim H‐s
Seoul National University Hospital
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Kim Hyo-soo
韓国
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Park Keun-Ho
Seoul National University Hospital
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Oh Byung-Hee
Seoul National University Hospital
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Choi Yun
Department Of Internal Medicine Seoul National University College Of Medicine
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Kang Hyun-jae
韓国
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Kang H‐j
Seoul National University Hospital
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Oh B‐h
Seoul National University Hospital
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Oh Byung-hee
韓国
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Park Y‐b
Division Of Cardiology Department Of Internal Medicine Seoul National University College Of Medicine
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Kim Ju
The Heart Center Of Chonnam National University Hospital
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Cho Young-seok
Department Of Internal Medicine Seoul National University College Of Medicine Seoul National Univers
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Kim Yong-jin
Division Of Cardiology Department Of Internal Medicine Seoul National University College Of Medicine
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Park Keun-ho
Department Of Laboratory Medicine Seoul National University College Of Medicine:seoul National Unive
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Park Keun-ho
韓国
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Choi Donghoong
Division Of Cardiology Severance Cardiovascular Hospital Yonsei University College Of Medicine
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JEONG Myung
The Heart Center of Chonnam National University Hospital
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CHO Jeong
The Heart Center of Chonnam National University Hospital
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CHO Dong
Chemical Engineering of Chonnam National University
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KANG Jung
The Heart Center of Chonnam National University Hospital
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PARK Kyung-Woo
Jeju self-government province
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CHO Young-Seok
Jeju self-government province
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KIM Hyo-Soo
Jeju self-government province
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Kim Yong-jin
Division Of Cardiology Yeungnam University Medical Center
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Kim Yong-seok
Seoul National University Bundang Hospital Cardiovascular Center
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Hong Taek
Division Of Cardiology Pusan National University Hospital
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Hong Taek
Division Of Cardiology Department Of Internal Medicine College Of Medicine Pusan National University
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Kang Jung
Division Of Cardiology Chonbuk National University Hospital
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Kim Kee
Division Of Cardiology Department Of Internal Medicine College Of Medicine Daegu Catholic University
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Park Hyo
韓国
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Park Hyo
Division Of Cardiology Department Of Internal Medicine College Of Medicine Seoul National University
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Jeong Myung-ho
Chonnam National University Hospital
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Park Young-bae
Division Of Cardiology Department Of Internal Medicine College Of Medicine Seoul National University
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Chae Shung
Kyungpook National University
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Jeong Myung
Yonsei University Wonju Hospital
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Oh Byung-hee
Division Of Cardiology Department Of Internal Medicine College Of Medicine Seoul National University
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Park Young
Division Of Cardiology Department Of Internal Medicine College Of Medicine Seoul National University
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Park Jin
Department Of Biochemistry Medical School Chonbuk National University
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Ahn Youngkeun
Department Of Cardiovascular Medicine Chonnam National University Medical School
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Choi Dong
Division Of Cardiology Yonsei University Severans Hospital
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Jeong Myung-ho
Division Of Cardiology Chonnam National University Hospital
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Cho Dong
Center For Functional Nano Fine Chemicals Chonnam National University
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Ahn Youngkeun
Heart Center Chonnam National University Hospital
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Choi Ji-yong
Division Of Cardiology Department Of Internal Medicine College Of Medicine Daegu Catholic University
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Nam Chang-wook
Division Of Cardiology Keimyung University Dongsan Medical Center
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Lee Wonjae
Division Of Cardiology Department Of Internal Medicine College Of Medicine Seoul National University
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Chae Shung
Division Of Cardiology Kyungpook National University Hospital
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Lee Jae-hwan
Division Of Cardiology Chungnam National University Hospital
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Kim Young
Division Of Applied Plant Science Agricultural Plant Stress Research Center
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Chae Jei
Division Of Cardiology Chonbuk National University Hospital
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Kim Hyo-soo
Cardiovascular Center And Department Of Internal Medicine Seoul National University Hospital
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Cho Jungsun
Heart Center Chonnam National University Hospital
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Park K‐w
Jeju Self-government Province
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Park Jin
Department Of Anatomy Ajou University School Of Medicine
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Cho Young-seok
Department Of Internal Medicine Seoul National University College Of Medicine Seoul National Univers
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Kim Young
Department Of Radiology Chonnam National University Hospital The Research Institute Of Medical Scien
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Kim Yong
Department Of Radiology Chonnam National University Hospital The Research Institute Of Medical Scien
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Kim Hyo-soo
Division Of Cardiology Department Of Internal Medicine College Of Medicine Seoul National University
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Cho Young-seok
Department Of Internal Medicine Seoul National University College Of Medicine Seoul National Univers
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Park Jin
Department Of Internal Medicine Sejong General Hospital
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Park Jin
Department of Advanced Materials Science and Engineering, Sungkyunkwan University, Suwon, Gyeonggi 440-746, Republic of Korea
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