Age-Related Differences in Intravascular Ultrasound Findings in 1,009 Coronary Artery Disease Patients
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概要
- 論文の詳細を見る
Background The aim of this study was to assess the age-related differences in intravascular ultrasound (IVUS) findings of target lesions in patients with coronary artery disease. Methods and Results The 1,009 patients who underwent IVUS imaging were grouped according to an increase of 10 years of age: Group I [<50 years (n=144)]; Group n [51-60 years (n=259)]; Group III [61-70 years (n=249)]; Group IV [71-80 years (n=264)]; and Group V [>80 years, (n=93)]. Calcified plaque (18%, 25%, 33%, 38%, and 46%, p<0.001) and negative remodeling (29%, 48%, 44%, 44%, and 66%, p<0.001) were most common, and reference segment plaque burden (35±11%, 35±10%, 39±10%, 38±10%, and 40±11%, p<0.001) was greatest in Group V. Plaque rupture (52%, 31%, 42%, 38%, and 20%, p=0.009) and thrombus (38%, 30%, 31%, 24%, and 11%, p=0.026) were most common in Group I. In the multiple logistic regression analysis, patient age was an independent predictor of calcified plaque (odds ratio (OR)=1.03, p=0.001), negative remodeling (OR=1.04, p=0.001), and mean reference segment plaque burden >50% (OR=1.03, p=0.006). Conclusion Elderly patients have more severe calcifications with negative remodeling and diffuse atherosclerosis, whereas younger patients have more unstable plaque morphology.
- 社団法人日本循環器学会の論文
- 2008-07-20
著者
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Ahn Young
The Heart Center Of Chonnam National University Hospital
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Kim Ju
The Heart Center Of Chonnam National University Hospital
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Moon Jae
The Heart Center Of Chonnam National University Hospital Cardiovascular Research Institute Of Chonna
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HONG Young
The Heart Center of Chonnam National University Hospital
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JEONG Myung
The Heart Center of Chonnam National University Hospital
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SIM Doo
The Heart Center of Chonnam National University Hospital
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YOON Nam
The Heart Center of Chonnam National University Hospital
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YOON Hyun
The Heart Center of Chonnam National University Hospital
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KIM Kye
The Heart Center of Chonnam National University Hospital
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PARK Hyung
The Heart Center of Chonnam National University Hospital
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AHN Youngkeun
The Heart Center of Chonnam National University Hospital
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CHO Jeong
The Heart Center of Chonnam National University Hospital
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PARK Jong
The Heart Center of Chonnam National University Hospital
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KANG Jung
The Heart Center of Chonnam National University Hospital
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Kim Kun
The Heart Center Of Chonnam National University Hospital
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Jeong Myung
Yonsei University Wonju Hospital
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Kim Yong
Cardiovascular Research Institute Chonnam National University
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Cho Jung
Chonnam National University Medical School
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Jeong Yun
Lab Of Stem Cell And Tumor Biology College Of Veterinary Medicine Seoul National University
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Ahn Youngkeun
Department Of Cardiovascular Medicine Chonnam National University Medical School
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Jeong Myung
The Heart Center Chonnam National University Hospital The Research Institute Of Medical Sciences Cho
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Chung Jong
The Heart Center of Chonnam National University Hospital
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Cho Jung
The Heart Center of Chonnam National University Hospital
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Ahn Youngkeun
Heart Center Chonnam National University Hospital
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Choi Ji-yong
Division Of Cardiology Department Of Internal Medicine College Of Medicine Daegu Catholic University
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Park Jong
The Heart Center Chonnam National University Hospital The Research Institute Of Medical Sciences Cho
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Kang Jung
The Heart Center Chonnam National University Hospital The Research Institute Of Medical Sciences Cho
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Kim Kyehun
Heart Center Chonnam National University Hospital
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Cho Jungsun
Heart Center Chonnam National University Hospital
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Jeong Myung
Department Of Cardiovascular Medicine Chonnam National University Medical School
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Hong Youngjoon
Heart Center Chonnam National University Hospital
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