Drug-Eluting vs. Bare-Metal Stents for Treatment of Acute Myocardial Infarction With Renal Insufficiency : Results From Korea Acute Myocardial Infarction Registry
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概要
- 論文の詳細を見る
Background: Patients with chronic kidney disease have had conflicting results between drug-eluting stents (DES) and bare-metal stents (BMS). The aim of the present study was to determine whether DES is preferable for the treatment of acute myocardial infarction (AMI) with renal insufficiency, and to elucidate the impact of diabetes mellitus (DM) on outcomes of each stent. Methods and Results: As a part of the Korea Acute Myocardial Infarction Registry (KAMIR), 2,175 AMI patients with renal insufficiency (glomerular filtration rate <60ml/min) comprising 208 patients with BMS and 1,967 DES implantation were selected. Primary outcome was major adverse cardiac event (MACE), defined as a composite of mortality, nonfatal myocardial infarction, and target lesion revascularization. In the overall population, the MACE rate at 1 year was significantly higher in the BMS group than that of DES (44% vs. 26%, P<0.05), which was mainly due to death rather than repeat intervention (44% vs. 26%, P<0.05). In the diabetic group with DES implantation, the MACE rate was higher compared with the DES group without DM, mainly due to repeat intervention (5% vs. 8%, P<0.05). Conclusions: In AMI patients with renal insufficiency, DES implantation exhibits a favorable 1-year clinical outcome than BMS implantation, and subgroup analysis for diabetic subjects showed worse outcomes in the DM group with implanted DES. (Circ J 2011; 75: 2798-2804)
- 社団法人 日本循環器学会の論文
- 2011-11-25
著者
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JEONG Myung
The Heart Center of Chonnam National University Hospital
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Bae Eun
Department Of Food And Nutrition Kyung Hee University
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Bae Eun
The Heart Center Of Chonnam National University Hospital Chonnam National University Research Instit
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Jeong Myung
Yonsei University Wonju Hospital
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Lim Sang
The Cardiovascular Center Of Korea University Anam Hospital
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Choi Joon
Department Of Forest Sciences And Research Institute For Agriculture And Life Science Seoul National
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Cho Kyung
Department Of Environmental Science And Engineering Ewha Womans University
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Ma Seong
Department Of Internal Medicine Chonnam National University Medical School
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Suh Sang
Department Of Environmental Horticulture Sangju National University
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Jeong Myungho
Heart Center Chonnam National University Hospital
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Kim Soo
Department Of Advanced Technology Fusion Konkuk University
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Lim Sang
Department Of Chemical Engineering Sungkyunkwan University
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Park Jeong
Department Of Basic Nursing Science And Institute For Nursing Science Keimyung University College Of
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Kim Soo
Department Of Internal Medicine Chonnam National University Medical School
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Jeong Myung
Department Of Cardiovascular Medicine Chonnam National University Medical School
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Choi Young
Department Of Biological Sciences Purdue University Calumet
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Kim Chang
Department Of Biochemistry University Of Oxford
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Choi Young
Department Of Internal Medicine Chonnam National University Medical School
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Suh Sang
Department Of Internal Medicine Chonnam National University Medical School
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Kim Chang
Department Of Internal Medicine Chonnam National University Medical School
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Lim Sang
Department Of Anesthesiology And Pain Medicine Korea University Guro Hospital
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Choi Joon
Department Of Internal Medicine Chonnam National University Medical School
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Cho Kyung
Department Of Internal Medicine Chonnam National University Medical School
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Jeong Myung
Department of Cardiology, Cardiovascular Center, Clinical Trial Center, Chonnam National University Hospital
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Cho Kyung
Department of Cardiology, Cardiovascular Center, Clinical Trial Center, Chonnam National University Hospital
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CHOI Young
Department of Agricultural Biotechnology, Seoul National University
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