Intensive Pharmacologic Treatment in Patients With Acute Non ST-Segment Elevation Myocardial Infarction Who Did Not Undergo Percutaneous Coronary Intervention
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概要
- 論文の詳細を見る
Background The aim of this study was to assess the impact of more aggressive pharmacological treatment on short-term clinical outcomes in patients with acute non ST-segment elevation myocardial infarction (NSTEMI) who do not undergo percutaneous coronary intervention (PCI). Methods and Results The 924 NSTEMI patients treated with early conservative strategy (69.2±12.5 years, 637 males) in 50 hospitals that were high-volume centers with facilities for primary PCI were recruited to the Korean Acute Myocardial Infarction Registry (KAMIR) from November 2005 to August 2007. For all patients, the pharmacotherapy index based on the use of drugs during hospital stay was assessed (range of points 0-10). Primary endpoint was the combined in-hospital mortality and morbidity and major adverse cardiac events during 1 month of clinical follow-up. Of the patients, data from 847 who were followed-up for 1 month after discharge were analyzed. The rate of the primary endpoint decreased with an increase of the pharmacotherapy index and this result was similar in the low- and high-risk groups. In the multivariate analysis, low pharmacotherapy index (≤4 points) was an independent predictor of the primary endpoint. Conclusions More intensive pharmacological treatment may improve short-term clinical outcomes in acute NSETMI patients who do not undergo PCI.
- 社団法人日本循環器学会の論文
- 2008-08-20
著者
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Ahn Young
The Heart Center Of Chonnam National University Hospital
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Koo Bon-Kwon
Cardiovascular Center, Seoul National University Hospital
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Rhew Jae
Jeonju Presbyterian Medical Center
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Koo Bon-kwon
Seoul National University Hospital
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Koo Bon
Heart Center Of Chonnam National University Hospital
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Chae In
Heart Center Of Chonnam National University Hospital
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Kim Ju
The Heart Center Of Chonnam National University Hospital
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JEONG Myung
Heart Center of Chonnam National University Hospital, Chonnam National University Research Institute
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Kim Yong-jin
Division Of Cardiology Department Of Internal Medicine Seoul National University College Of Medicine
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Choi Donghoong
Division Of Cardiology Severance Cardiovascular Hospital Yonsei University College Of Medicine
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JEONG Myung
The Heart Center of Chonnam National University Hospital
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CHO Jeong
The Heart Center of Chonnam National University Hospital
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CHO Dong
Chemical Engineering of Chonnam National University
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KANG Jung
The Heart Center of Chonnam National University Hospital
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Kim Chong
Kyunghee University
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Kim Yong-jin
Division Of Cardiology Yeungnam University Medical Center
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Hong Taek
Division Of Cardiology Pusan National University Hospital
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Kang Jung
Division Of Cardiology Chonbuk National University Hospital
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Kim Kee
Division Of Cardiology Department Of Internal Medicine College Of Medicine Daegu Catholic University
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Chae Shung
Kyungpook National University
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Hur Seung
Keimyung University
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Seong In
Chungnam National University
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Cho Myeong
Chungbuk National University
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Jang Yang
Yonsei University
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Jeong Myung
Yonsei University Wonju Hospital
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Oh Seouk
Gachon University Gil Medical Center
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Jeong Hae
Heart Center of Chonnam National University Hospital
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Ahn Young
Heart Center of Chonnam National University Hospital
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Chae Shung
Heart Center of Chonnam National University Hospital
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Kim Jong
Heart Center of Chonnam National University Hospital
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Seong In
Heart Center of Chonnam National University Hospital
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Kim Young
Heart Center of Chonnam National University Hospital
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Hur Seung
Heart Center of Chonnam National University Hospital
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Choi Dong
Heart Center of Chonnam National University Hospital
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Hong Taek
Heart Center of Chonnam National University Hospital
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Yoon Jung
Heart Center of Chonnam National University Hospital
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Rhew Jae
Heart Center of Chonnam National University Hospital
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Chae Jei
Heart Center of Chonnam National University Hospital
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Kim Doo
Heart Center of Chonnam National University Hospital
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Kim Byung
Heart Center of Chonnam National University Hospital
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Lee Nae
Heart Center of Chonnam National University Hospital
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Hwang Jin
Heart Center of Chonnam National University Hospital
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Oh Seok
Heart Center of Chonnam National University Hospital
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Cho Myeong
Heart Center of Chonnam National University Hospital
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Kim Kee
Heart Center of Chonnam National University Hospital
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Jeong Kyoung
Heart Center of Chonnam National University Hospital
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Lee Myoung
Heart Center of Chonnam National University Hospital
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Kim Chong
Heart Center of Chonnam National University Hospital
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Chung Wook
Heart Center of Chonnam National University Hospital
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Kim Yong
Cardiovascular Research Institute Chonnam National University
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Ahn Youngkeun
Department Of Cardiovascular Medicine Chonnam National University Medical School
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Oh Seok
Wonkwang University Hospital
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Choi Dong
Division Of Cardiology Yonsei University Severans Hospital
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Jeong Myung
Heart Center Chonnam National University Hospital
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Chae In-ho
Cardiovascular Center Seoul National University Hospital
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Cho Dong
Center For Functional Nano Fine Chemicals Chonnam National University
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Ahn Youngkeun
Heart Center Chonnam National University Hospital
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Ahn Young
Heart Center Chonnam National University Hospital
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Choi Ji-yong
Division Of Cardiology Department Of Internal Medicine College Of Medicine Daegu Catholic University
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Hur Seung-ho
Department Of Cardiology Keimyung University Dongsan Medical Center
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Chae Shung
Division Of Cardiology Kyungpook National University Hospital
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Kim Chong
Kyunghee University Hospital
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Cho Jungsun
Heart Center Chonnam National University Hospital
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Jeong Myung
Department Of Cardiovascular Medicine Chonnam National University Medical School
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Jang Yang
Wonju Christian Hospital
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Korea Acute
Korean Circulation Society
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