Correlation of Serial Cardiac Magnetic Resonance Imaging Parameters With Early Resolution of ST-Segment Elevation After Primary Percutaneous Coronary Intervention
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概要
- 論文の詳細を見る
Background The aim of the present study was to determine whether the parameters of cardiac magnetic resonance imaging (CMRI) might correlate with early ST-segment resolution (STR) after primary percutaneous coronary intervention (PCI) in ST-elevation myocardial infarction (STEMI). Methods and Results CMRI was performed in 45 STEMI patients (age: 56.6±13.0 years) at 8.2±8.0 days (early phase) and 3.3±1.1 months (late phase) after successful PCI. CMRI parameters were compared between 2 groups: ≥70% STR (group 1, n=21) and <70% STR (group 2, n=24). Both groups had similar baseline characteristics, except for a higher frequency of ≥2 myocardial blush grade and shorter pain-to-balloon time in group 1. Early-phase CMRI showed that persistent microvascular obstruction (PMO) (38.1% vs 91.7%, p<0.001) occurred less frequently and the percent infarct mass against total left ventricular (LV) mass (17.7±8.7% vs 29.1±13.4%, p=0.001) was smaller in group 1. Late-phase CMRI revealed a significant increase in LV end-diastolic volume (-1.5±8.7 vs 14.5±25.5 ml, p=0.026) and reduced ejection fraction (55.0±9.9% vs 47.8±11.1%, p=0.027) in group 2. Conclusions CMRI demonstrated that early STR might be related to PMO and infarct size, and predicts LV dysfunction and adverse LV remodeling. Also, early-phase CMRI findings are comparable to late-phase CMRI in association with early STR. (Circ J 2008; 72: 1621 - 1626)
- 社団法人日本循環器学会の論文
- 2008-09-20
著者
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Ahn Young
The Heart Center Of Chonnam National University Hospital
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KIM Jung-Sun
Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine
-
KO Young-Guk
Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine
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CHOI Donghoon
Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine
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JANG Yangsoo
Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine
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Kim Ju
The Heart Center Of Chonnam National University Hospital
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Choi Donghoong
Division Of Cardiology Severance Cardiovascular Hospital Yonsei University College Of Medicine
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Jang Yangsoo
Division Of Cardiology Severance Cardiovascular Hospital Yonsei University College Of Medicine
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Kim Jung-sun
Division Of Cardiology Severance Cardiovascular Hospital Yonsei University College Of Medicine
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Kim Jung-sun
Division Of Cardiology Department Of Laboratory Medicine Yonsei University College Of Medicine
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Ko Young-guk
Division Of Cardiology Severance Cardiovascular Hospital Yonsei University College Of Medicine
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Kim Young
Department Of Electronics Engineering Korea Advance Intitute Of Science & Technology
-
Jang Yang
Yonsei University
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Yoon Jung
Heart Center of Chonnam National University Hospital
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Kim Yong
Cardiovascular Research Institute Chonnam National University
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Kim Young
Department Of Diagnostic Radiology Yonsei University College Of Medicine
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Kim Young
Department Of Agricultural Chemistry The University Of Tokyo
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KIM Jong-Youn
The first two authors equally contributed to this study
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Yoon Se-Jung
Division of Cardiology, NHIC Ilsan Hospital
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Moon Jae-Youn
Division of Cardiology, Yonsei Cardiovascular Center, Yonsei University College of Medicine
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Choi Byoung
Department of Diagnostic Radiology, Yonsei University College of Medicine
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Yoon Se-jung
Division Of Cardiology Nhic Ilsan Hospital
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Yoon Se-jung
Division Of Cardiology Department Of Laboratory Medicine Yonsei University College Of Medicine
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Choi Byoung
Department Of Diagnostic Radiology Yonsei University College Of Medicine
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Choi Byoung
Department Of Chemical Technology Taejon National University Of Technology Korea
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Moon Jae-youn
Division Of Cardiology Yonsei Cardiovascular Center Yonsei University College Of Medicine
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Jang Yang
Wonju Christian Hospital
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