2407 MEMS技術を用いた心筋細胞の材料特性を測定するデバイスの開発(J22-2 材料特性計測とマイクロ機構,J22 マイクロメカトロニクス,2005年度年次大会)

概要

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We study on the measurement of mechanical properties of a living cardiac myocyte. Micro mechanical sensors were made of PDMS using MEMS technique. The device consists of micro posts which work as vertical cantilevers measuring local contractile forces of a single myocyte. The generated force is calculated from the displacement of the top of the post. We also propose the device with through holes on the micro channel to apply negative pressure to the cell. And this device has additional capability to measure the cell responses to the physical and chemical effects simultaneously with molecular localization in the cell. This approach has the potential to measure the physiological properties of a single myocyte to develop a bio-simulator model.
一般社団法人日本機械学会の論文
2005-09-18