Difference of Survivals due to DMA Ploidy Patterns in Colorectal Cancer : Effects of Mitotic Activity and Clinicopathologic Variables on the Survivals
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概要
- 論文の詳細を見る
Survivals due to the difference of DNA ploidy patterns were examined in 34 colorectal cancer patients, and the effects of prognostic variables including mitotic activity and clinicopathology of cancer lesions on the survivals were analyzed. The survival curve of 14 patients with diploid cancer was significantly better than that of 20 patients with aneuploid cancer, and the 9-year survival rate was 68.4 % in the former and 33.8 % in the latter. The mean (26.1 %o) of mitotic indices in the aneuploid cancers was significantly higher than that (18.7 %o) in the diploid cancers. Although no significant difference in 7 out of 9 clinocopathologic variables was found between both DNA ploidy patterns, node metastasis and advanced stages in the aneuploid cancers were significantly more than those in the diploid cancers. These results clearly indicate that the survival of patients with diploid cancer is better than that of patients with aneuploid cancer. Difference of the survivals between them seems to be caused by the difference of mitotic activity, node metastasis and stage classification.
- 神戸大学の論文
- 1994-12-28
著者
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Nakamura Takeshi
Department Of Gastroenterological Surgery Kobe University Graduate School Of Medical Sciences
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Nakamura Takeshi
First Department Of Surgery Kobe University School Of Medicine
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NAKAE Shiro
First Department of Surgery, Kobe University School of Medicine
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Nakae Shiro
First Department Of Surgery Kobe University School Of Medicine
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Tabuchi Yoshiki
Faculty Of Health Science Kobe University School Of Medicine
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