Inhibitory Effects of a Cyclosporin Derivative, SDZ PSC 833, on Transport of Doxorubicin and Vinblastine via Human P-Glycoprotein
スポンサーリンク
概要
- 論文の詳細を見る
- 1998-11-30
著者
-
TANIGAWARA Yusuke
Department of Pharmacy, School of Medicine, Keio University
-
KU Yonson
First Division, Department of Surgery, Kobe University School of Medicine
-
KURODA Yoshikazu
First Division, Department of Surgery, Kobe University School of Medicine
-
OKUMURA Katsuhiko
Department of Hospital Pharmacy, Kobe University School of Medicine
-
Ku Yonson
神戸大学 医学研究科肝胆膵外科
-
Kimura T
Kobe University Graduate School Of Medicine
-
Ueda Kazumitsu
Laboratory Of Cellular Biochemistry Division Of Applied Life Sciences Graduate School Of Agriculture
-
Takara Kohji
Department of Hospital Pharmacy, Faculty of Pharmaceutical Sciences, Kyoto Pharmaceutical University
-
Ku Yonson
First Department Of Surgery Kobe University School Of Medicine
-
Ku Yonson
First Department Of Surgery School Of Medicine Kobe University
-
Okumura K
Department Of Clinical Evaluation Of Pharmacotherapy Kobe University Graduate School Of Medicine
-
Takara Kohji
Department Of Hospital Pharmacy Faculty Of Pharmaceutical Sciences Kyoto Pharmaceutical University
-
Takara Kohji
Department Of Clinical Pharmacy Faculty Of Pharmaceutical Sciences Kyoto Pharmaceutical University
-
Takara Kohji
Department Of Hospital Pharmacy School Of Medicine Kobe University
-
Yamauchi Aiko
Faculty Of Pharmaceutical Sciences Kobe-gakuin University
-
Yamauchi Aiko
Faculty Of Pharmaceutical Sciences Tokushima University
-
KOMADA Fusao
Department of Drug Informatics, Faculty of Pharmaceutical Sciences, Josai University
-
Kamiyama Fumio
京都大学再生医科学研究所
-
Kodama Fusao
Cosmed Pharmaceutical Co. Ltd.
-
KUSUNOKI Nobuya
First Department of Surgery School of Medicine, Kobe University
-
SAITOH Yohichi
First Department of Surgery School of Medicine, Kobe University
-
Tanigawara Yusuke
Department Of Clinical Pharmacokinetics And Pharmacodynamics School Of Medicine Keio University
-
Komada Fusao
Department Of Pharmacy Kyoto University Hospital Faculty Of Medicine Kyoto University
-
Kuroda Yoshikazu
First Department Of Surgery Faculty Of Medicine Kobe University
-
Kusunoki Nobuya
First Department Of Surgery School Of Medicine Kobe University
-
Okumura Katsuhiko
Department Of Clinical Evaluation Of Pharmacotherapy Kobe University Graduate School Of Medicine
-
Okumura Katsuhiko
Department Of Hospital Pharmacy Kyoto Pharmaceutical University:department Of Hospital Pharmacy Kobe
-
Ueda Kazumitsu
Laboratory Of Biochemistry Department Of Agricultural Chemistry Kyoto University
-
Ueda Kazumitsu
Laboratory Of Biochemistry Department Of Applied Life Science Kyoto University Graduate School
-
Kuroda Yoshikazu
First Department Of Surgery School Of Medicine Kobe University
-
Komada F
Department Of Pharmacy Kobe University School Of Medicine
-
Saitoh Yohichi
First Department Of Surgery School Of Medicine Kobe University
-
Nakamura Takeshi
Department Of Gastroenterological Surgery Kobe University Graduate School Of Medical Sciences
-
Koishi Tomokazu
Department Of Hospital Pharmacy Faculty Of Pharmaceutical Sciences Kyoto Pharmaceutical University
関連論文
- 高血圧症患者におけるオルメサルタン及びアゼルニジピンの比較薬力学 : 母集団薬物動態 / 薬力学解析
- Histological study of PIVKA-II expression in hepatocellular carcinoma and adenomatous hyperplasia
- Inhibitory Role of Plasminogen Activator Inhibitor-1 in Invasion and Proliferation of HLE Hepatocellular Carcinoma Cells
- S22-3 Pharmaco-proteomics and metabolomics for personalized medicine(FIP joint conference S22 International Conference Supported by FIP and JSPHCS Individualized Medicine: Bridging between Scientific and Clinical Studies)
- Association of Cumulative Cyclosporine Dose with Its Irreversible Nephrotoxicity in Japanese Patients with Pediatric-Onset Autoimmune Diseases(Biopharmacy)
- Phase I Study of Intravenous PSC-833 and Doxorubicin: Reversal of Multidrug Resistance
- MEAN RESIDENCE TIME IN ORGANS IN TOXICOKINETIC STUDIES
- Splenic Atrophy in Experimental Severe Acute Pancreatitis
- Hydronephrosis Associated with Acute Pancreatitis
- Duodenal Necrosis Associated with Acute Pancreatitis
- Inhibitory Effect of Vacuolating Toxin of Helicobacter pylori on Enzyme Secretion from Rat Pancreatic Acini
- Carcinosarcoma of the gallbladder with chondroid differentiation
- 健康成人における塩酸ランジオロールの母集団薬物動態モデルの構築
- Reversal Effects of Ca2+ Antagonists on Multidrug Resistance via Down-regulation of MDR1 mRNA
- Three-Dimensional, but not Two-Dimensional, Culture Results in Tumor Growth Enhancement after Exposure to Anticancer Drugs
- Knock-down of Sorcin Induces Up-regulation of MDR1 in HeLa Cells(Molecular and Cell Biology)
- Effects of Reactive Oxygen Species on Cell Proliferation and Death in HeLa Cells and Its MDR1-Overexpressing Derivative Cell Line
- Effects of carvedilol on MDR1-mediated multidrug resistance : comparison with verapamil
- Effects of St John's Wort and Hypericin on Cytotoxicity of Anticancer Drugs
- Cytotoxic Effects of 27 Anticancer Drugs in HeLa and MDR1-Overexpressing Derivative Cell Lines
- Antiproliferative Activity of Rhinacanthus nasutus (L.) KURZ Extracts and the Active Moiety, Rhinacanthin C(Pharmacology)
- High Expression of Thymidylate Synthase Leads to Resistance to 5-Fluorouracil in Biliary Tract Carcinoma in vitro
- Intradermal Concentration of Hydroquinone after Application of Hydroquinone Ointments Is Higher than Its Cytotoxic Concentration(Biopharmacy)
- Different Contribution of CYP2C19 in the in Vitro Metabolism of Three Proton Pump Inhibitors
- A Multi-institutional Study on Adjuvant Chemotherapy for the Prevention of Post-operative Liver Metastases in Colorectal Cancer Patients : Comparison Between Hepatic Arterial and Portal Adriamycin Plus Oral UFT Administration
- Combined Gastrectomy with Adjacent Organs in T4 Gastric Cancer : Therapeutic Results and Indication
- Appendiceal Intussusception Induced by Tubulovillous Adenoma with Carcinoma in Situ : Report of a Case
- Immunohistochemical P 53 Protein Expression in Advanced Colorectal Cancer Lesions : No Association with Prognostic Variables or Survival
- Possible Role of Heat Shock Protein 60 in Reducing Ischemic-Reperfusion Injury in Canine Pancreas Grafts After Preservation by the Two-Layer Method
- Superiority of Mild Hypothermic (20℃) Preservation for Pancreatic Microvasculature Using the Two-Layer Storage Method
- Evidence of Protein Synthesis During Resuscitation of Ischemically Damaged Canine Pancreas by the Two-Layer Method
- Recovery of Pancreatic Tissue Perfusion and ATP Tissue Level After Reperfusion in Canine Pancreas Grafts Preserved by the Two-Layer Method
- Centrifugal Pump-Assisted Venous Bypass Between the Superior Mesenteric Vein and the Umbilical Vein During Portal Vein Resection
- Resected Acinar Cell Carcinoma of the Pancreas with Tumor Thrombus Extending into the Main Portal Vein : Report of a Case
- Percutaneous Hepatic Venous Isolation and Extracorporeal Charcoal Hemoperfusion for High-Dose Intraarterial Chemotherapy in Patients with Colorectal Hepatic Metastases
- A Novel Paper Cuff for Vascular Reconstruction in Canine Liver Transplantation
- Adenine Nucleotide Metabolism of Canine Pancreas Graft Preserved by the Two-Layer (Euro-Collins' Solution/Perfluorochemical) Method after Reperfusion
- Suppression of Human Pancreatic Carcinoma Cell Growth and Invasion by Epigallocatechin-3-Gallate
- MDR1 Haplotype Frequencies in Japanese and Caucasian, and in Japanese Patients with Colorectal Cancer and Esophageal Cancer
- MDR1 C3435T Polymorphism Is Predictive of Later Onset of Ulcerative Colitis in Japanese(Biopharmacy)
- Reversal Effects of Antifungal Drugs on Multidrug Resistance in MDR1-Overexpressing HeLa Cells
- Genetic analysis of a local recurrent tumor after colonic polypectomy
- IL-1β Genotype-Related Effect of Prednisolone on IL-1β Production in Human Peripheral Blood Mononuclear Cells under Acute Inflammation(Pharmacology)
- Genetic polymorphisms associated with adverse events and elimination of methotrexate in childhood acute lymphoblastic leukemia and malignant lymphoma
- Effect of Therapeutic Moderate Hypothermia on Multi-drug Resistance Protein 1-Mediated Transepithelial Transport of Drugs
- Comparison of Synthetic DNA Templates with Authentic cDNA Templates in Terms of Quantification by Real-Time Quantitative Reverse Transcription Polymerase Chain Reaction(Analytical Biochemistry)
- 電流検出方式DNAチップを用いた複数遺伝子型同時判定法のMDR1遺伝子への応用
- Surgical Significance of Telomerase Activity in Noncancerous Liver Tissue from Patients with Hepatocellular Carcinoma
- Comparative Study of Superoxide Dismutase in Normal and Hereditary Cataract (UPL) Rats
- Single-institute phase 2 study of thalidomide treatment for refractory or relapsed multiple myeloma : Prognostic factors and unique toxicity profile
- Effects of Polymorphisms of MDR1, MRP1, and MRP2 Genes on Their mRNA Expression Levels in Duodenal Enterocytes of Healthy Japanese Subjects(Biopharmacy)
- MDR1-Mediated Interaction of Digoxin with Antiarrhythmic or Antianginal Drugs
- Factors Influencing the Prediction of Steady State Concentrations of Digoxin
- Interaction of Docetaxel ("Taxotere") with Human P-Glycoprotein
- Cellular Pharmacokinetic Aspects of Reversal Effect of Itraconazole on P-Glycoprotein-Mediated Resistance of Anticancer Drugs
- Inhibitory Effects of a Cyclosporin Derivative, SDZ PSC 833, on Transport of Doxorubicin and Vinblastine via Human P-Glycoprotein
- Thalidomide for the Treatment of Refractory Multiple Myeloma : Association of Plasma Concentrations of Thalidomide and Angiogenic Growth Factors with Clinical Outcome
- The Effect of Preservation Temperature and Period on Resuscitation of the Ischemically Damaged Canine Pancreas during Preservation by the Two-Layer (University of Wisconsin Solution/Perfluorochemical) Method
- P-gp誘導 Caco-2 細胞 : P-gp高感度 Assay System の構築
- URINARY EXCRETION AND DIURETIC RESPONSE TO FUROSEMIDE IN RATS AND HUMANS WITH RENAL INSUFFICIENCY
- FATE OF PORCINE AND HUMAN INSULIN AT THE SUBCUTANEOUS INJECTION SITE. II. IN VITRO DEGRADATION OF INSULINS IN THE SUBCUTANEOUS TISSUE OF THE RAT
- FATE OF PORCINE AND HUMAN INSULIN AT THE SUBCUTANEOUS INJECTION SITE. I. DEGRADATION AND ABSORPTION OF INSULINS IN THE RAT
- FATE OF PORCINE AND HUMAN INSULIN IN SUBCUTANEOUSLY ADMINISTERED SITE
- Pharmacokinetics of Pirarubicin in Pediatric Patients
- Determining the Optimum Dose for the Intravenous Administration of Nicardipine in the Treatment of Acute Heart Failure : A Multicenter Study
- N-Acetyltransferase2 Genotype Correlated with Isoniazid Acetylation in Japanese Tuberculous Patients
- Effects of Secretable SOD Delivered by Genetically Modified Cells on Xanthine/Xanthine Oxidase and Paraquat-Induced Cytotoxicity in Vitro
- Effects of Cu, Zn-Superoxide Dismutase Delivered by Genetically Modified Skin Fibroblasts on Cold-Induced Skin Edema in Rats
- Protective Effect of Transfection with Secretable Superoxide Dismutase (SOD) (a Signal Sequence-SOD Fusion Protein Coding cDNA) Expression Vector on Superoxide Anion-Induced Cytotoxicity in Vitro)
- Effect of Transfection with a Superoxide Dismutase Expression Plasmid on Xanthine/Xanthine Oxidase-Induced Cytotoxicity in Cultured Rat Lung Cells
- Pharmaceutical Studies for Gene Therapy : Expression of Human Cu, Zn-Superoxide Dismutase Gene Transfected by Lipofection in Rat Skin Fibroblasts
- Effect of Clarithromycin on the Bioavailability of Cyclosporin in Rats
- Effect of Transfection with Superoxide Dismutase Expression Plasmid on Superoxide Anion Induced Cytotoxicity in Cultured Rat Lung Cells
- Pharmacokinetics of Zonisamide ; Saturable Distribution into Human and Rat Erythrocytes and into Rat Brain
- Improvement in Wound Healing by Epidermal Growth Factor (EGF) Ointment. II. Effect of Protease Inhibitor, Nafamostat, on Stabilization and Efficacy of EGF in Burn
- Effects of Various Storage Conditions and Alterations of Antioxidant Contents on Chromatic Aberration of Hydroquinone Ointment(Biopharmacy)
- Effect of Serum Triglyceride Concentration on the Fluctuation of Whole Blood Concentration of Cyclosporin A in Patients
- Pharmacodynamic analysis of vancomycin effect alone and with serum proteins : using a novel in vitro model
- Macrocystic serous cystadenoma of the pancreas
- N-Acetyltransferase 2 Genotype-Related Sulfapyridine Acetylation and Its Adverse Events
- Optimal Dose of Omeprazole for CYP2C19 Extensive Metabolizers in Anti-Helicobacter pylori Therapy : Pharmacokinetic Considerations
- N-Acetyltransferase 2 Genotype Correlates with Sulfasarazine Pharmacokinetics after Multiple Dosing in Healthy Japanese Subjects
- Sufficient effect of 1-week omeprazole and amoxicillin dual treatment for Helicobacter pylori eradication in cytochrome P450 2C19 poor metabolizers
- ミカファンギンの小児適応のためのポピュレーションPK解析
- Linear Pharmacokinetics of Micafungin and Its Active Metabolites in Japanese Pediatric Patients with Fungal Infections(Biopharmacy)
- Pharmaceutical and Clinical Assessment of Hydroquinone Ointment Prepared by Extemporaneous Nonsterile Compounding
- A novel proteomic approach to determine possible biomarkers for acute rejection after small bowel transplantation
- Discovery of new biomarkers for acute rejection and therapeutic effect of immunosuppressive drugs in the rat liver transplantation : a comprehensive gene expression analysis
- A major influence of CYP2C19 genotype on the steady-state concentration of N-desmethylclobazam
- Influence of N-Terminal Peptide and Oligosaccharide on the Clearance of t-PA
- An Experimental Study of Regional Chemotherapy Using CDDP-Loaded Microspheres for Esophageal Cancer
- The Novel Anticancer Drug KRN5500 Interacts with, but is Hardly Transported by, Human P-Glycoprotein
- Influence of Sugar Chain on Fibrin Affinity of Recombinat t-PA
- New biomarkers for acute rejection and therapeutic effect of immunosuppressive drugs in the rat cardiac transplantation by cDNA microarray analysis
- Spontaneous Splenic Rupture During the Course of a Rubella Infection : Report of a Case
- Relationship between Pharmacokinetic Parameters and Occurrence of Adverse Events in Clinical Trials Performed in Europe and United States for an Angiotensin II Receptor Antagonist, Telmisartan
- Pharmacokinetic Comparison of an Angiotensin II Receptor Antagonist, Telmisartan, in Japanese and Western Hypertensive Patients Using Population Pharmacokinetic Method
- Phorbol Myristate Acetate Stimulates Degradation of a Structural Analogue of Platelet-Activating Factor to a Neutral Lipid in Human Leukemic K562 Cells : Relevance to the Release of Lipids(Biochemistry/Molecular Biology)
- Prediction of the efficacy and safety of pioglitazone in patients with type 2 diabetes mellitus
- Serum cystatin C as a new marker for determining the optimal dosage of renally excreted drugs