Prediction of the efficacy and safety of pioglitazone in patients with type 2 diabetes mellitus
スポンサーリンク
概要
- 論文の詳細を見る
- 2005-01-01
著者
-
TANIGAWARA Yusuke
Department of Pharmacy, School of Medicine, Keio University
-
Kadowaki Takashi
Department of Health Science, Shiga University of Medical Science
-
Kadowaki Takashi
Department Of Cardiovascular Medicine Graduate School Of Medicine University Of Tokyo
-
Kasai Hidefumi
Department Of Dermatology Tohoku University School Of Medicine
-
Kasai Hidefumi
Department Of Pharmacy School Of Medicine Keio University
-
Tanigawara Yusuke
Department Of Clinical Pharmacokinetics And Pharmacodynamics School Of Medicine Keio University
-
Kadowaki Takashi
Department Of Metabolic Diseases Graduate School Of Medicine The University Of Tokyo
-
Kadowaki Takashi
Department Of Cardiology Kawasaki Medical School
関連論文
- 高血圧症患者におけるオルメサルタン及びアゼルニジピンの比較薬力学 : 母集団薬物動態 / 薬力学解析
- Marital Status and Cardiovascular Risk Factors among Middle-aged Japanese Male Workers : The High-risk and Population Strategy for Occupational Health Promotion (HIPOP-OHP) Study
- PE-410 Associations of CRP and Fibrinogen with Subclinical Atherosclerosis in Whites in US, Japanese-American in Hawaii and Japanese in Japan : ERA-JUMP Study(PE069,Preventive Medicine/Epidemiology/Education 2 (H),Poster Session (English),The 73rd Annual
- PE-410 Associations of CRP and Fibrinogen with Subclinical Atherosclerosis in Whites in US, Japanese-American in Hawaii and Japanese in Japan : ERA-JUMP Study(PE069,Preventive Medicine/Epidemiology/Education 2 (H),Poster Session (English),The 73rd Annual
- S22-3 Pharmaco-proteomics and metabolomics for personalized medicine(FIP joint conference S22 International Conference Supported by FIP and JSPHCS Individualized Medicine: Bridging between Scientific and Clinical Studies)
- Molecular Mechanism of Moderate Insulin Resistance in Adiponectin-Knockout Mice
- Adipose Tissue Remodeling and Malfunctioning in Obesity Revealed by in vivo Molecular Imaging
- Determination of Endogenous Levels of Retinoic Acid Isomers in Type II Diabetes Mellitus Patients. Possible Correlation with HbAlc Values(Analytical Biochemistry)
- A Japanese Case of Congenital Hyperinsulinism with Hyperammonemia Due to a Mutation in Glutamate Dehydrogenase (GLUD1) Gene
- Phase I Study of Intravenous PSC-833 and Doxorubicin: Reversal of Multidrug Resistance
- Relationship between Metabolic Syndrome and Trp64Arg Polymorphism of the β3-Adrenergic Receptor Gene in a General Sample : The Shigaraki Study
- PJ-689 Relationship between a Metabolic Syndrome and the Polymorphism of the Beta3 Adrenergic Receptor Gene in a General Sample (S-town study)(Diabetes/Obesity/Metabolic syndrome-13 (H) PJ116,Poster Session (Japanese),The 70th Anniversary Annual Scientifi
- PJ-689 Relationship between a Metabolic Syndrome and the Polymorphism of the Beta3 Adrenergic Receptor Gene in a General Sample (S-town study)(Diabetes/Obesity/Metabolic syndrome-13 (H) PJ116,Poster Session (Japanese),The 70th Anniversary Annual Scientifi
- Genetic Variations of Mrf-2/Arid5b Confer Risk of Coronary Atherosclerosis in the Japanese Population
- MEAN RESIDENCE TIME IN ORGANS IN TOXICOKINETIC STUDIES
- Impact of Increased PPARγ Activity in Adipocytes in vivo on Adiposity, Insulin Sensitivity and the Effects of Rosiglitazone Treatment
- Peroxisome Proliferator-Activated Receptor γ (PPARγ) Suppresses Colonic Epithelial Cell Turnover and Colon Carcinogenesis Through Inhibition of the β-Catenin / T Cell Factor (TCF) Pathway
- FRS-060 SUMOylation of KLF5 is a key molecular switch of transcriptional regulatory programs of lipid metabolism(New Insights into Metabolic Syndrome(02)(H),Featured Research Session,The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- Association of TCF7L2 polymorphisms with susceptibility to type 2 diabetes in 4,087 Japanese subjects
- PE-537 Identification of the Novel MEF2-Kruppel-like Factor 5 (KLF5) Network That Associates with Cardiovascular Disease(Molecular biology, vascular-3, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PE-411 KLF5 Controls Metabolic Stress Response in Metabolic Syndrome and Cardiovascular Disease(Diabetes/Obesity/Metabolic syndrome-05, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Impact of Hypertension on Medical Economics : A 10-Year Follow-Up Study of National Health Insurance in Shiga, Japan
- Combined Analysis of Polymorphisms in Angiotensinogen and Adducin Genes and Their Effects on Hypertension in a Japanese Sample : The Shigaraki Study
- Prognostic Value of Q Wave for Cardiovascular Death in a 19-Year Prospective Study of the Japanese General Population
- Relationships between Family Histories of Stroke and of Hypertension and Stroke Mortality : NIPPON DATA80, 1980-1999
- Associations of Obesity Measures With Metabolic Risk Factors in a Community-Based Population in Japan
- PE-167 The Relationship between Alcohol Intake and Coronary Calcification in Middle-aged Healthy Japaense Men(Atherosclerosis, clinical-7 (H) PE28,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- 健康成人における塩酸ランジオロールの母集団薬物動態モデルの構築
- Reversal Effects of Ca2+ Antagonists on Multidrug Resistance via Down-regulation of MDR1 mRNA
- PJ-296 Heterozygous PPAR γ Deficient Mice Showed Increased Neointima Formation with Vascular Smooth Muscle Cell Proliferation in Response to Cuff Injury(Atherosclerosis, Basic 3 (IHD) : PJ50)(Poster Session (Japanese))
- Lack of Insulin Receptor Substrate-2 Is a Link between Insulin Resistance and an Increased Intima of the Vessel in Mice
- Prevalence of Vitreous Hemorrhage Following Coronary Revascularization in Patients With Diabetic Retinopathy
- Obese adipose tissue remodeling, malfunctioning, and chronic inflammation visualized by in vivo molecular imaging
- FRS-077 Regulated Cholesterol Efflux with Adiponectin and Its Receptors in HEK293T Cells(FRS16,Basic Mechanisms of Lipid Disorders and Metabolic Syndrome (H),Featured Research Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulatio
- Diminished Left Ventricular Function and Coronary Perivascular Fibrosis Associated with Insulin Resistance do not Require Insulin Receptor Substarte-1 Mediated Signaling
- Maturity-onset Diabetes of the Young Resulting from a Novel Mutation in the HNF-4α Gene
- Inhibition of Peroxisome Proliferator-Activated Receptor γ Promotes Tumorigenesis Through Activation of the β-Catenin/T Cell Factor (TCF) Pathway in the Mouse Intestine
- PE-324 Adiponectin May Effect on Angiotensin II Stimulations(Vascular smooth muscles-2 (H) PE54,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- Reduced Adiponectin Level Is Associated With Severity of Coronary Artery Disease
- Single-institute phase 2 study of thalidomide treatment for refractory or relapsed multiple myeloma : Prognostic factors and unique toxicity profile
- Psychological Factors, Coffee and Risk of Diabetes Mellitus among Middle-Aged Japanese : a Population-Based Prospective Study in the JPHC Study Cohort
- MDR1-Mediated Interaction of Digoxin with Antiarrhythmic or Antianginal Drugs
- Factors Influencing the Prediction of Steady State Concentrations of Digoxin
- Interaction of Docetaxel ("Taxotere") with Human P-Glycoprotein
- Cellular Pharmacokinetic Aspects of Reversal Effect of Itraconazole on P-Glycoprotein-Mediated Resistance of Anticancer Drugs
- Inhibitory Effects of a Cyclosporin Derivative, SDZ PSC 833, on Transport of Doxorubicin and Vinblastine via Human P-Glycoprotein
- Kruppel-like Transcription Factor KLF5 is a Key Regulator Governing Adipocyte Differentiation(Metabolic Syndrome (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Thalidomide for the Treatment of Refractory Multiple Myeloma : Association of Plasma Concentrations of Thalidomide and Angiogenic Growth Factors with Clinical Outcome
- Genetic variants in the calpain-10 gene and the development of type 2 diabetes in the Japanese population
- OE-220 Induction of Adipose PAI-1 Independent of Insulin Receptor Substrate-1 is the Major Determinant of Hypofibrinolysis in Insulin Resistance(Thromboembolism/Antithrombotic therapy/Thrombolysis-1 (H) OE37,Oral Presentation (English),The 70th Anniversar
- OE-119 Identification of Insulin Receptor Substrate Family Proteins Mediating PAI-1 Production in Cardiac and Adipose Tissues From IRS-1 Null Mice(Diabetes/Obesity/Metabolic syndrome-1 (H) OE20,Oral Presentation (English),The 70th Anniversary Annual Scien
- Induction of Adipose PAI-1 by Hyperinsulinemia in Vivo is the Major Determinant of Hypofibrinolysis in Obesity and Doesn't Require IRS-1(Thrombosis/Thrombolysis 2 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Low-Risk Profile for Cardiovascular Disease and Mortality in Japanese
- OE-090 Should Alcohol Intake be Restricted in Diabetic Men? : NIPPON DATA80(Preventive medicine/Epidemiology/Education(01)(H),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- Joint Impact of Smoking and Hypertension on Cardiovascular Disease and All-Cause Mortality in Japan : NIPPON DATA80, a 19-Year Follow-Up
- Exenatide Exhibits Dose-Dependent Effects on Glycemic Control over 12 Weeks in Japanese Patients with Suboptimally Controlled Type 2 Diabetes
- Development of a Food Frequency and Quantity Method for Assessing Dietary Habits of Japanese Individuals : Comparison with Results from 24hr Recall Dietary Survey
- Antibody-mediated Insulin Resistance Treated by Cessation of Insulin Administration
- OJ-046 KLF5 Plays Pivotal Roles in Pathogenesis of both Metabolic Syndrome and Vascular Disease(Diabetes/Obesity/Metabolic syndrome-3 (H) OJ8,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- OE-316 Kruppel-like family of transcription factor 5 is required for adipocyte differentiation(Diabetes/Obesity 2 (H) : OE40)(Oral Presentation (English))
- N-Acetyltransferase2 Genotype Correlated with Isoniazid Acetylation in Japanese Tuberculous Patients
- Effects of Secretable SOD Delivered by Genetically Modified Cells on Xanthine/Xanthine Oxidase and Paraquat-Induced Cytotoxicity in Vitro
- Effects of Cu, Zn-Superoxide Dismutase Delivered by Genetically Modified Skin Fibroblasts on Cold-Induced Skin Edema in Rats
- Effect of Transfection with a Superoxide Dismutase Expression Plasmid on Xanthine/Xanthine Oxidase-Induced Cytotoxicity in Cultured Rat Lung Cells
- Pharmaceutical Studies for Gene Therapy : Expression of Human Cu, Zn-Superoxide Dismutase Gene Transfected by Lipofection in Rat Skin Fibroblasts
- Effect of Transfection with Superoxide Dismutase Expression Plasmid on Superoxide Anion Induced Cytotoxicity in Cultured Rat Lung Cells
- Establishment of a method of anonymization of DNA samples in genetic research
- C57BL/6JJclを遺伝的背景に持つIRS2欠損マウスの効率的な繁殖方法の検討
- Association of Lipoprotein-associated Phospholipase A2 with Coronary Calcification among American and Japanese Men
- OE-318 Maintenance of Cardiac and Adipose PAI-1 Expression Despite the Lack of IRS-1 : a Knockout Mouse Study(Diabetes/Obesity 2 (H) : OE40)(Oral Presentation (English))
- Electrocardiogram Screening for Left High R-Wave Predicts Cardiovascular Death in a Japanese Community-Based Population : NIPPON DATA90
- Selective Ablation of IRS-1 Decreases Cardiac Contractility without Attenuating PAI-1 Expression or Perivascular Fibrosis
- Pharmacodynamic analysis of vancomycin effect alone and with serum proteins : using a novel in vitro model
- Phenotypes of IRS-2 Deficient Mice Produced by Reproductive Technology are Stable
- Role of suppressors of cytokine signaling SOCS-1 and SOCS-3 in hepatic steatosis and the metabolic syndrome
- Sufficient effect of 1-week omeprazole and amoxicillin dual treatment for Helicobacter pylori eradication in cytochrome P450 2C19 poor metabolizers
- 5 Establishment of clinical database system and identification of genetic factors contributing to the pathogenesis of atheroscherosis(Symposium 4 (SY4) (IHD) : Molecular Mechanism of Atherosclerosis)(Special Program)
- ミカファンギンの小児適応のためのポピュレーションPK解析
- Linear Pharmacokinetics of Micafungin and Its Active Metabolites in Japanese Pediatric Patients with Fungal Infections(Biopharmacy)
- A novel proteomic approach to determine possible biomarkers for acute rejection after small bowel transplantation
- Discovery of new biomarkers for acute rejection and therapeutic effect of immunosuppressive drugs in the rat liver transplantation : a comprehensive gene expression analysis
- Combined Cardiovascular Risk Factors and Outcome : NIPPON DATA80, 1980-1994
- Chronic Kidney Disease is a Risk Factor for Cardiovascular Death in a Community-Based Population in Japan : NIPPON DATA90
- OE-230 Adiponectin and its Receptors Increase Cholesterol Efflux in HEK293T Cells(Metabolism/Biochemistry/Energetics(01)(M),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- A major influence of CYP2C19 genotype on the steady-state concentration of N-desmethylclobazam
- Influence of N-Terminal Peptide and Oligosaccharide on the Clearance of t-PA
- Single-nucleotide polymorphisms in the 17β-hydroxysteroid dehydrogenase genes might predict the risk of side-effects of estramustine phosphate sodium in prostate cancer patients
- Nuclear Receptors as Targets for Drug Development : Molecular Mechanisms for Regulation of Obesity and Insulin Resistance by Peroxisome Proliferator-Activated Receptor γ, CREB-Binding Protein, and Adiponectin
- How Controlling of Hypertension Might Matter
- Effect of Combined Cardiovascular Risk Factors on Individual and Population Medical Expenditures : A 10-Year Cohort Study of National Health Insurance in a Japanese Population
- Life expectancy among Japanese of different smoking status in Japan: NIPPON DATA80
- The Novel Anticancer Drug KRN5500 Interacts with, but is Hardly Transported by, Human P-Glycoprotein
- Influence of Sugar Chain on Fibrin Affinity of Recombinat t-PA
- Insights into Molecular Pathogenesis of Type 2 Diabetes from Knockout Mouse Models
- New biomarkers for acute rejection and therapeutic effect of immunosuppressive drugs in the rat cardiac transplantation by cDNA microarray analysis
- Relationship between Pharmacokinetic Parameters and Occurrence of Adverse Events in Clinical Trials Performed in Europe and United States for an Angiotensin II Receptor Antagonist, Telmisartan
- Pharmacokinetic Comparison of an Angiotensin II Receptor Antagonist, Telmisartan, in Japanese and Western Hypertensive Patients Using Population Pharmacokinetic Method
- Phorbol Myristate Acetate Stimulates Degradation of a Structural Analogue of Platelet-Activating Factor to a Neutral Lipid in Human Leukemic K562 Cells : Relevance to the Release of Lipids(Biochemistry/Molecular Biology)
- Prediction of the efficacy and safety of pioglitazone in patients with type 2 diabetes mellitus
- Serum cystatin C as a new marker for determining the optimal dosage of renally excreted drugs