Exenatide Exhibits Dose-Dependent Effects on Glycemic Control over 12 Weeks in Japanese Patients with Suboptimally Controlled Type 2 Diabetes

スポンサーリンク

概要

• 論文の詳細を見る
• 2009-06-20

著者

• Kadowaki Takashi

  Department of Health Science, Shiga University of Medical Science

• Kadowaki Takashi

  Department Of Cardiovascular Medicine Graduate School Of Medicine University Of Tokyo

• Kadowaki Takashi

  Department Of Metabolic Diseases Graduate School Of Medicine University Of Tokyo

• Namba Mitsuyoshi

  Division Of Diabetes And Metabolism Department Of Internal Medicine Hyogo College Of Medicine

• YAMAMURA AYUKO

  Lilly Research Laboratories Japan, Eli Lilly Japan KK, Sannomiya Plaza Bldg.

• SOWA HIDEAKI

  Lilly Research Laboratories Japan, Eli Lilly Japan KK, Sannomiya Plaza Bldg.

• WOLKA ANNE

  Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center

• BRODOWS ROBERT

  Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center

• Wolka Anne

  Lilly Research Laboratories Eli Lilly And Company Lilly Corporate Center

• Sowa Hideaki

  Lilly Research Laboratories Japan Eli Lilly Japan Kk Sannomiya Plaza Bldg.

• Brodows Robert

  Lilly Research Laboratories Eli Lilly And Company Lilly Corporate Center

• Yamamura Ayuko

  Lilly Research Laboratories Japan Eli Lilly Japan K.k.

• Yamamura Ayuko

  Lilly Research Laboratories Japan Eli Lilly Japan Kk Sannomiya Plaza Bldg.

• Sowa Hideaki

  Lilly Res. Laboratories Japan Eli Lilly Japan Kk

• Kadowaki Takashi

  Department Of Cardiology Kawasaki Medical School

関連論文

• Marital Status and Cardiovascular Risk Factors among Middle-aged Japanese Male Workers : The High-risk and Population Strategy for Occupational Health Promotion (HIPOP-OHP) Study
• Effects of Medication on Cardiovascular Events in the Japanese Coronary Artery Disease (JCAD) Study
• PE-410 Associations of CRP and Fibrinogen with Subclinical Atherosclerosis in Whites in US, Japanese-American in Hawaii and Japanese in Japan : ERA-JUMP Study(PE069,Preventive Medicine/Epidemiology/Education 2 (H),Poster Session (English),The 73rd Annual
• PE-410 Associations of CRP and Fibrinogen with Subclinical Atherosclerosis in Whites in US, Japanese-American in Hawaii and Japanese in Japan : ERA-JUMP Study(PE069,Preventive Medicine/Epidemiology/Education 2 (H),Poster Session (English),The 73rd Annual
• Effects of Nicorandil on Cardiovascular Events in Patients With Coronary Artery Disease in The Japanese Coronary Artery Disease (JCAD) Study
• Gender Differences in Patients With Coronary Artery Disease in Japan : The Japanese Coronary Artery Disease Study (The JCAD Study)
• Elevated Serum Uric Acid is an Independent Predictor for Cardiovascular Events in Patients With Severe Coronary Artery Stenosis : Subanalysis of the Japanese Coronary Artery Disease (JCAD) Study
• OJ-160 Comparison of Risk Factors between Angiographically Diffuse versus Focal Stenosis in the Patients Enrolled in Japanese Coronary Artery Disease (JCAD) Study(OJ27,Coronary Circulation/Chronic Coronary Disease (Basic/Clinical) (IHD),Oral Presentation
• OE-390 Association between Angiographical Assessment of Luminal Narrowing and Recurrence of Cardiovascular Events : Substudy of Japanese Coronary Artery Disease (JCAD) Study(OE66,Atherosclerosis (Clinical/Pathophysiology) (IHD),Oral Presentation (English)
• FRS-087 The Impact of Diabetes on the Prognosis of Japanese Patients with Coronary Artery Disease(FRS18,New Insights into Metabolic Syndrome (H),Featured Research Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• Elevated Serum C-Reactive Protein Levels Predict Cardiovascular Events in the Japanese Coronary Artery Disease (JCAD) Study(Epidemiology)
• Demographics and Changes in Medical/Interventional Treatment of Coronary Artery Disease Patients Over a 3.5-Year Period in Japan : The Japanese Coronary Artery Disease Study: Trend Examination
• Molecular Mechanism of Moderate Insulin Resistance in Adiponectin-Knockout Mice
• Rationale and Design of a Study to Examine Lower Targets for Low-Density Lipoprotein-Cholesterol and Blood Pressure in Coronary Artery Disease Patients : The Japanese Coronary Artery Disease Study II (JCADII)
• OJ-217 Genetic Variations of Mrf-2/Arid5B Confers Risk of Coronary Atherosclerosis in the Japanese Population(Genetics/Genetically engineered models/Gene therapy-2(H/M), The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• Adipose Tissue Remodeling and Malfunctioning in Obesity Revealed by in vivo Molecular Imaging
• PJ-482 The Polymorphism in the Adiponectin Gene is Associated with Susceptibility to Coronary Artery Disease(Atherosclerosis, clinical-11 (H) PJ81,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society
• Determination of Endogenous Levels of Retinoic Acid Isomers in Type II Diabetes Mellitus Patients. Possible Correlation with HbAlc Values(Analytical Biochemistry)
• A Japanese Case of Congenital Hyperinsulinism with Hyperammonemia Due to a Mutation in Glutamate Dehydrogenase (GLUD1) Gene
• Relationship between Metabolic Syndrome and Trp64Arg Polymorphism of the β3-Adrenergic Receptor Gene in a General Sample : The Shigaraki Study
• PJ-689 Relationship between a Metabolic Syndrome and the Polymorphism of the Beta3 Adrenergic Receptor Gene in a General Sample (S-town study)(Diabetes/Obesity/Metabolic syndrome-13 (H) PJ116,Poster Session (Japanese),The 70th Anniversary Annual Scientifi
• PJ-689 Relationship between a Metabolic Syndrome and the Polymorphism of the Beta3 Adrenergic Receptor Gene in a General Sample (S-town study)(Diabetes/Obesity/Metabolic syndrome-13 (H) PJ116,Poster Session (Japanese),The 70th Anniversary Annual Scientifi
• Genetic Variations of Mrf-2/Arid5b Confer Risk of Coronary Atherosclerosis in the Japanese Population
• Beta-Blocker Prescription Among Japanese Cardiologists and Its Effect on Various Outcomes
• Relationship Between Renal Dysfunction and Severity of Coronary Artery Disease in Japanese Patients
• PJ-038 Cystatin C Predicts Severity of Coronary Artery Disease Even in Patients without Chronic Kidney Disease (CKD)(PJ007,Kidney/Renal Circulation/CKD 1 (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• Impact of Increased PPARγ Activity in Adipocytes in vivo on Adiposity, Insulin Sensitivity and the Effects of Rosiglitazone Treatment
• Peroxisome Proliferator-Activated Receptor γ (PPARγ) Suppresses Colonic Epithelial Cell Turnover and Colon Carcinogenesis Through Inhibition of the β-Catenin / T Cell Factor (TCF) Pathway
• FRS-060 SUMOylation of KLF5 is a key molecular switch of transcriptional regulatory programs of lipid metabolism(New Insights into Metabolic Syndrome(02)(H),Featured Research Session,The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• Association of TCF7L2 polymorphisms with susceptibility to type 2 diabetes in 4,087 Japanese subjects
• PE-537 Identification of the Novel MEF2-Kruppel-like Factor 5 (KLF5) Network That Associates with Cardiovascular Disease(Molecular biology, vascular-3, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PE-411 KLF5 Controls Metabolic Stress Response in Metabolic Syndrome and Cardiovascular Disease(Diabetes/Obesity/Metabolic syndrome-05, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• Impact of Hypertension on Medical Economics : A 10-Year Follow-Up Study of National Health Insurance in Shiga, Japan
• Combined Analysis of Polymorphisms in Angiotensinogen and Adducin Genes and Their Effects on Hypertension in a Japanese Sample : The Shigaraki Study
• Prognostic Value of Q Wave for Cardiovascular Death in a 19-Year Prospective Study of the Japanese General Population
• Relationships between Family Histories of Stroke and of Hypertension and Stroke Mortality : NIPPON DATA80, 1980-1999
• Associations of Obesity Measures With Metabolic Risk Factors in a Community-Based Population in Japan
• PE-167 The Relationship between Alcohol Intake and Coronary Calcification in Middle-aged Healthy Japaense Men(Atherosclerosis, clinical-7 (H) PE28,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-296 Heterozygous PPAR γ Deficient Mice Showed Increased Neointima Formation with Vascular Smooth Muscle Cell Proliferation in Response to Cuff Injury(Atherosclerosis, Basic 3 (IHD) : PJ50)(Poster Session (Japanese))
• Lack of Insulin Receptor Substrate-2 Is a Link between Insulin Resistance and an Increased Intima of the Vessel in Mice
• Vascular Intima Formation in Insulin Receptor Substrate-2 Deficient Mice
• Prevalence of Vitreous Hemorrhage Following Coronary Revascularization in Patients With Diabetic Retinopathy
• Obese adipose tissue remodeling, malfunctioning, and chronic inflammation visualized by in vivo molecular imaging
• FRS-077 Regulated Cholesterol Efflux with Adiponectin and Its Receptors in HEK293T Cells(FRS16,Basic Mechanisms of Lipid Disorders and Metabolic Syndrome (H),Featured Research Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulatio
• Diminished Left Ventricular Function and Coronary Perivascular Fibrosis Associated with Insulin Resistance do not Require Insulin Receptor Substarte-1 Mediated Signaling
• Maturity-onset Diabetes of the Young Resulting from a Novel Mutation in the HNF-4α Gene
• Inhibition of Peroxisome Proliferator-Activated Receptor γ Promotes Tumorigenesis Through Activation of the β-Catenin/T Cell Factor (TCF) Pathway in the Mouse Intestine
• PE-324 Adiponectin May Effect on Angiotensin II Stimulations(Vascular smooth muscles-2 (H) PE54,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• Reduced Adiponectin Level Is Associated With Severity of Coronary Artery Disease
• Psychological Factors, Coffee and Risk of Diabetes Mellitus among Middle-Aged Japanese : a Population-Based Prospective Study in the JPHC Study Cohort
• Polymorphism of the Angiotensin Converting Enzyme Gene and Blood Pressure in a Japanese General Population (the Shigaraki Study)
• Kruppel-like Transcription Factor KLF5 is a Key Regulator Governing Adipocyte Differentiation(Metabolic Syndrome (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Genetic variants in the calpain-10 gene and the development of type 2 diabetes in the Japanese population
• OE-220 Induction of Adipose PAI-1 Independent of Insulin Receptor Substrate-1 is the Major Determinant of Hypofibrinolysis in Insulin Resistance(Thromboembolism/Antithrombotic therapy/Thrombolysis-1 (H) OE37,Oral Presentation (English),The 70th Anniversar
• OE-119 Identification of Insulin Receptor Substrate Family Proteins Mediating PAI-1 Production in Cardiac and Adipose Tissues From IRS-1 Null Mice(Diabetes/Obesity/Metabolic syndrome-1 (H) OE20,Oral Presentation (English),The 70th Anniversary Annual Scien
• Induction of Adipose PAI-1 by Hyperinsulinemia in Vivo is the Major Determinant of Hypofibrinolysis in Obesity and Doesn't Require IRS-1(Thrombosis/Thrombolysis 2 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Low-Risk Profile for Cardiovascular Disease and Mortality in Japanese
• OE-090 Should Alcohol Intake be Restricted in Diabetic Men? : NIPPON DATA80(Preventive medicine/Epidemiology/Education(01)(H),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• Joint Impact of Smoking and Hypertension on Cardiovascular Disease and All-Cause Mortality in Japan : NIPPON DATA80, a 19-Year Follow-Up
• Exenatide Exhibits Dose-Dependent Effects on Glycemic Control over 12 Weeks in Japanese Patients with Suboptimally Controlled Type 2 Diabetes
• Development of a Food Frequency and Quantity Method for Assessing Dietary Habits of Japanese Individuals : Comparison with Results from 24hr Recall Dietary Survey
• Antibody-mediated Insulin Resistance Treated by Cessation of Insulin Administration
• OJ-046 KLF5 Plays Pivotal Roles in Pathogenesis of both Metabolic Syndrome and Vascular Disease(Diabetes/Obesity/Metabolic syndrome-3 (H) OJ8,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• OE-316 Kruppel-like family of transcription factor 5 is required for adipocyte differentiation(Diabetes/Obesity 2 (H) : OE40)(Oral Presentation (English))
• The Mechanism of Insulin-induced Signal Transduction Mediated by the Insulin Receptor Substrate Family
• Establishment of a method of anonymization of DNA samples in genetic research
• C57BL/6JJclを遺伝的背景に持つIRS2欠損マウスの効率的な繁殖方法の検討
• Clinical Experience with Cryopreserved Allografts for Aortic Infection
• Association of Lipoprotein-associated Phospholipase A2 with Coronary Calcification among American and Japanese Men
• OE-318 Maintenance of Cardiac and Adipose PAI-1 Expression Despite the Lack of IRS-1 : a Knockout Mouse Study(Diabetes/Obesity 2 (H) : OE40)(Oral Presentation (English))
• Electrocardiogram Screening for Left High R-Wave Predicts Cardiovascular Death in a Japanese Community-Based Population : NIPPON DATA90
• Selective Ablation of IRS-1 Decreases Cardiac Contractility without Attenuating PAI-1 Expression or Perivascular Fibrosis
• Phenotypes of IRS-2 Deficient Mice Produced by Reproductive Technology are Stable
• Role of suppressors of cytokine signaling SOCS-1 and SOCS-3 in hepatic steatosis and the metabolic syndrome
• 5 Establishment of clinical database system and identification of genetic factors contributing to the pathogenesis of atheroscherosis(Symposium 4 (SY4) (IHD) : Molecular Mechanism of Atherosclerosis)(Special Program)
• Lack of B Cell Leakiness in BALB/cA-nu, scid Double Mutant Mice
• Pneumocystis carinii Cysts are Susceptible to Inactivation by Chemical Disinfectants
• Combined Cardiovascular Risk Factors and Outcome : NIPPON DATA80, 1980-1994
• Chronic Kidney Disease is a Risk Factor for Cardiovascular Death in a Community-Based Population in Japan : NIPPON DATA90
• OE-230 Adiponectin and its Receptors Increase Cholesterol Efflux in HEK293T Cells(Metabolism/Biochemistry/Energetics(01)(M),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• Plasma Cystatin C Concentration Reflects the Severity of Coronary Artery Disease in Patients Without Chronic Kidney Disease
• Single-nucleotide polymorphisms in the 17β-hydroxysteroid dehydrogenase genes might predict the risk of side-effects of estramustine phosphate sodium in prostate cancer patients
• Nuclear Receptors as Targets for Drug Development : Molecular Mechanisms for Regulation of Obesity and Insulin Resistance by Peroxisome Proliferator-Activated Receptor γ, CREB-Binding Protein, and Adiponectin
• How Controlling of Hypertension Might Matter
• Effect of Combined Cardiovascular Risk Factors on Individual and Population Medical Expenditures : A 10-Year Cohort Study of National Health Insurance in a Japanese Population
• Life expectancy among Japanese of different smoking status in Japan: NIPPON DATA80
• Insights into Molecular Pathogenesis of Type 2 Diabetes from Knockout Mouse Models
• The Proportion of Individuals with Alcohol-Induced Hypertension among Total Hypertensives in a General Japanese Population : NIPPON DATA90
• Polymorphism of the Angiotensinogen Gene and Hypertension in a Japanese General Population (the Shigaraki Study)
• Role of Mitochondrial NADH Shuttle System in Acute Amylase Secretion by Acetylcholine from Mouse Pancreatic Acinar Cells
• The Evaluation of Materials to Provide Health-Related Information as a Population Strategy in the Worksite : The High-Risk and Population Strategy for Occupational Health Promotion (HIPOP-OHP) Study(Special Issue)
• Effectiveness of a Low-Intensity Intra-Worksite Intervention on Smoking Cessation in Japanese Employees : A Three-Year Intervention Trial
• Prediction of the efficacy and safety of pioglitazone in patients with type 2 diabetes mellitus
• Prevalence of Vitreous Hemorrhage Following Coronary Revascularization in Patients With Diabetic Retinopathy
• Methodological Issues for a Large-Scale Intervention Trial of Lifestyle Modification : Interim Assessment of the High-Risk and Population Strategy for Occupational Health Promotion (HIPOP-OHP) Study(Special Issue)
• Effectiveness of Annual Interventions for Smoking Cessation in an Occupational Setting in Japan(Special Issue)
• Maturity-onset Diabetes of the Young Resulting from a Novel Mutation in the HNF-4α Gene
• Adiponectin receptors are downregulated in human gastric cancer
• Epidemiologic Study of the Association of Low-Km Mitochondrial Acetaldehyde Dehydrogenase Genotypes with Blood Pressure Level and the Prevalence of Hypertension in a General Population
• Non-Invasive Measurement of Brachial-Ankle Pulse Wave Velocity Is Associated with Serum C-Reactive Protein but Not with α-Tocopherol in Japanese Middle-Aged Male Workers

もっと見る 閉じる

スポンサーリンク