On the Synthesis of Uridylyl-(3'→5')-uridine
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概要
- 論文の詳細を見る
Uridylyl-(3'→5')-uridine (UpU) was synthesized via two different routes, i.e. by condensation of 2', 5'-di-O-trityluridine (I) with 2', 3'-di-O-acetyluridine 5'-phosphate (IV) (Route A) and by condensation of 2', 3'-di-O-acetyluridine (VI) with 2', 5'-di-O-trityluridine 3'-phosphate (II) (Route B). The acid treatments to remove trityl groups were performed with 80% acetic acid at both 37° and 100° in several time intervals. The yields of the final product, UpU, and the amounts of uridylyl-(2'→5')-uridine contained in the UpU were compared.
- 社団法人日本薬学会の論文
- 1964-12-25
著者
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早津 彦哉
Faculty of Pharmaceutical Sciences, University of Tokyo
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浮田 忠之進
Faculty of Pharmaceutical Sciences, University of Tokyo
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武田 寧
東京大学薬学部薬害研究施設
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武田 寧
Faculty of Pharmaceutical Sciences, University of Tokyo
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武田 寧
国立衛生研究所
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早津 彦哉
Faculty Of Pharmaceutical Sciences Okayama University
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浮田 忠之進
Faculty Of Pharmaceutical Sciences The University Of Tokyo
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早津 彦哉
Faculty of Pharmaceutical Sciences, Okayama University
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