Synthesis of 1-(β-D-Ribofuranosyl) urea and Related Compounds.

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概要

• 論文の詳細を見る

• 1-(β-D-Ribofuranosyl) urea (VII) was synthesized via. 2,3,5-tri-O-benzoyl-β-D-ribofuranosyl isocyanate (II) and 1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl) urea (V). One of the intermediate, V, which is an important starting material for the synthesis of ribonucleosides, was obtained in a yield of 70.5% by direct ammonolysis at 0°of the reaction mixture of 2,3,5-tri-O-benzoyl-D-ribofuranosyl chloride and silver isocyanate. The structure of V was confirmed by converting it to (β-D-ribofuranosyl) thymine.

• 社団法人日本薬学会の論文
• 1964-04-25

著者

• 浜田 昭

  Faculty Of Pharmaceutical Sciences University Of Tokyo

• 浮田 忠之進

  Faculty of Pharmaceutical Sciences, University of Tokyo

• 吉田 光昭

  Faculty of Pharmaceutical Science, University of Tokyo

• 吉田 光昭

  Faculty Of Pharmaceutical Sciences University Of Tokyo

• 浮田 忠之進

  Faculty Of Pharmaceutical Sciences The University Of Tokyo

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