Organic Phosphates. X. Several 2,3-Cyclic Phosphates of D-Ribofuranoside and their Properties as Substrate for Ribonuclease.
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概要
- 論文の詳細を見る
To find the minimum structural requirement in the substrate for pancreatic ribonuclease (RNase-I-A), 5-O-benzyl-D-ribofuranoside 2,3-cyclic phosphate (VI), and methyl α- and β-D-ribofuranoside 2,3-cyclic phosphates (IX and X) were synthesized and submitted to hydrolysis with this enzyme. No evidence was observed for hydrolysis of these cyclic phosphates to the corresponding 3-phosphates by the RNase and the results showed that more specially arranged atom grouping is required at 1-position of D-ribofuranoside 2,3-cyclic phosphate for this enzymatic hydrolysis.
- 社団法人日本薬学会の論文
- 1961-03-25
著者
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入江 昌親
Faculty of Pharmaceutical Sciences, Hoshi University
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入江 昌親
Faculty Of Pharmaceutical Sciences University Of Tokyo
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浮田 忠之進
Faculty of Pharmaceutical Sciences, University of Tokyo
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浮田 忠之進
Faculty Of Pharmaceutical Sciences The University Of Tokyo
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