Some Attempts on Substitution of 2'-Position of Uridine with Thiol Group.
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概要
- 論文の詳細を見る
The reactions of 2,2'-anhydrouridine (I) with hydrogen sulfide (Reaction A) and of I, 3', 5'-di-O-benzoyl-2,2'-anhydrouridine (III) and 1-(3', 5'-di-O-benzoyl-2'-methanesulfonyl-β-D-arabinofuranosyl) uracil (V) with thiobenzoate or xanthogenate nucleophiles (Reactions B), were investigated with the purpose of introducing thiol substituents at the 2'-position. The Reaction A afforded 1-β-D-arabinofuranosyl-2-thiouracil (II) as only sulfur containing product and the Reactions B gave no sulfur containing product but resulted in a partial liberation of uracil.
- 公益社団法人日本薬学会の論文
- 1967-10-25
著者
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関谷 剛男
Faculty Of Pharmaceutical Sciences The University Of Tokyo
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浮田 忠之進
Faculty of Pharmaceutical Sciences, University of Tokyo
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浮田 忠之進
Faculty Of Pharmaceutical Sciences The University Of Tokyo
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