UDP-GLUCURONYLTRANSFERASE ACTIVITIES OF RABBIT LIVER MICROSOMES FOR CANNABINOIDS
スポンサーリンク
概要
- 論文の詳細を見る
UDP-glucuronyltransferase activities for Δ^8-tetrahydrocannabinol, 11-hydroxy-Δ^8-tetrahydrocannabinol, cannabidiol and cannabinol were examined using liver microsomes of rabbits. The activities for cannabidiol and cannabinol were 2.5 and 19 times higher, respectively, than those for Δ^8-tetrahydrocannabinol and 11-hydroxy-Δ^8-tetrahydrocannabinol. Thus, the present study supports the view that glucuronide formation plays an important role in the metabolism of cannabinol, but does only a minor role in that of Δ^8-tetrahydrocannabinol and 11-hydroxy-Δ^8-tetrahydrocannabinol.
- 社団法人日本薬学会の論文
著者
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YOSHIMURA HIDETOSHI
Faculty of Pharmaceutical Sciences, Kyushu University
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YAMAMOTO Ikuo
School of Pharmaceutical Sciences, Kyushu University of Health and Welfare
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OGURI Kazuta
Faculty of Pharmaceutical Sciences, Kyushu University
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Yamamoto Ikuo
北陸大学 薬 衛化
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Yamamoto Ikuo
Department Of Hygienic Chemistry Faculty Of Pharmaceutical Sciences Hokuriku University
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WATANABE KAZUHITO
School of Pharmacy, Hokuriku University
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Yoshimura Hidetoshi
Faculty Of Pharmaceutical Sciences Kyushu University
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Oguri Kazuta
Faculty Of Pharmaceutical Sciences Kyushu University
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Oguri Kazuta
School Of Pharmacy Hokuriku University
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Watanabe Kazuhito
Faculty Of Pharmaceutical Sciences Kyushu University
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Yamamoto Ikuo
School Of Pharmaceutical Sciences Kyushu University Of Health And Welfare
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