OXYGEN-INSENSITIVE NITROFURAN REDUCTASES IN SALMONELLA TYPHIMURIUM TA100
スポンサーリンク
概要
- 論文の詳細を見る
The present study demonstrated by DEAE-cellulose column chromatography that oxygen-insensitive nitrofuran reductases in Salmonella typhimurium TA100 consisted of at least two reductases, NADPH-and NAD (P) H-linked enzymes. The NADPH-and NADH-linked activities of the latter enzyme seemed to originate from a single enzyme, because both activities were similarly inactivated by heat and urea treatments, and also inhibited by dicumarol. On the other hand, the NADPH-linked enzyme was less sensitive to heat, urea and dicumarol. Furthermore, the study showed that the NAD (P) H-linked enzyme was a flavoenzyme which could be inactivated by dialysis against 1 M potassium bromide and reactivated by FMN.
- 公益社団法人日本薬学会の論文
著者
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Doi Takayoshi
Present Address : Central Research Division Takeda Chemical Industries Ltd.
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Tatsumi Kiyoshi
Institute Of Pharmaceutical Sciences Hiroshima University School Of Medicine
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YOSHIMURA HIDETOSHI
Faculty of Pharmaceutical Sciences, Kyushu University
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KOGA HIDEO
Faculty of Pharmaceutical Sciences, Kyushu University
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HORIUCHI TADAO
Faculty of Pharmaceutical Sciences, Kyushu University
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TATSUMI KIYOSHI
Present address
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Yoshimura Hidetoshi
Faculty Of Pharmaceutical Sciences Kyushu University
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Koga Hideo
Faculty Of Pharmaceutical Sciences Kyushu University
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Horiuchi Tadao
Faculty Of Pharmaceutical Sciences Kyushu University
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