TOXICOLOGICAL ASSESSMENT OF POLYCHLORINATED DIBENZOFURANS (PCDF). I. RELATIONSHIP BETWEEN INDUCTIVE EFFECTS ON HEPATIC ENZYMES AND TOXICITIES OF PURE PCDF CONGENERS RETAINED IN YUSHO PATIENTS
スポンサーリンク
概要
著者
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Nagata Kiyoshi
九州大学 薬
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Nagata Kiyoshi
Faculty Of Pharmaceutical Sciences Kyushu University
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YOSHIMURA HIDETOSHI
Faculty of Pharmaceutical Sciences, Kyushu University
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MASUDA YOSHITO
Daiichi College of Pharmaceutical Sciences
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KUROKI HIROAKI
Daiichi College of Pharmaceutical Sciences
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Yoshimura Hidetoshi
Faculty Of Pharmaceutical Sciences Kyushu University
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Yoshihara Shinchi
Faculty Of Pharmaceutical Sciences Kyushu University
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Yoshihara Shinichi
Faculty Of Pharmaceutical Sciences Kyushu University
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Yoshihara S
Department Of Xenobiotic Metabolism And Molecular Toxicology Graduate School Of Biomedical Science H
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Masuda Yoshito
Daiichi Coll. Of Pharm. Sci.
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Nagata K
Faculty Of Pharmaceutical Sciences Kyushu University
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Yoshihara Shinichi
Faculty Of Pharmaceutical Sciences Kyushu University:(present Address)institute Of Pharmaceutical Sc
関連論文
- FURTHER STUDIES ON SULFOXIDE-REDUCING ENZYME SYSTEM
- STUDIES ON ENZYMIC REDUCTION OF NITRO COMPOUNDS
- COMPOSITION AND PROPERTIES OF SULFOXIDE-REDUCING ENZYME SYSTEMS
- SULFOXIDE-REDUCING ENZYME SYSTEMS
- METABOLISM IN VITRO OF SULINDAC. SULFOXIDE-REDUCING ENZYME SYSTEMS IN GUINEA PIG LIVER
- STUDIES ON METABOLIC ACTIVATION OF NITROFURANS : FORMATION OF ACTIVE METABOLITES AND THEIR BINDING TO CYSTEINE AND GLUTATHIONE
- RELATIONSHIP BETWEEN BIOLOGICAL ACTIVITIES AND ENZYMATIC REDUCTION OF NITROFURAN DERIVATIVES
- Site-Selective Oxidation of Strychnine by Phenobarbital Inducible Cytochrome P-450
- SITE-SELECTIVE OXIDATION OF STRYCHNINE BY PHENOBARBITAL INDUCIBLE CYTOCHROME P-450
- Species Difference in Metabolism of Strychnine with Liver Microsomes of Mice, Rats, Guinea Pigs, Rabbits and Dogs
- METABOLIC FATE OF STRYCHNINE IN VITRO
- MECHANISM OF SLEEP-PROLONGATING EFFECT OF Δ^8-TETRAHYDROCANNABINOL (Δ^8-THC) AND ITS METABOLITES
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- UDP-GLUCURONYLTRANSFERASE ACTIVITIES OF RABBIT LIVER MICROSOMES FOR CANNABINOIDS
- METABOLIC CONVERSION OF Δ^8-TETRAHYDROCANNABINOL (Δ^8-THC) TO Δ^8-THC-11-OIC ACID AND ITS PHARMACOLOGICAL IMPLICATIONS
- METABOLISM OF 11-HYDROXY-Δ^8-THC TO 11-OXO-Δ^8THC IN RATS (The Fourth Meeting for the Study of Toxic Effect)
- Inhibitory Effect of Cannabidiol Hydroxy-quinone, and Oxidative Product of Cannabidiol, on the Hepatic Microsomal Drug-Metabolizing Enzymes of Mice
- INTERACTION OF CANNABINOIDS WITH HEPATIC MICROSOMAL DRUG-METABOLIZING ENZYME SYSTEM IN THE RAT
- EFFECTS OF TWO CANNABINOIDS ON HEPATIC MICROSOMAL CYTOCHROME P-450
- METABOLIC ACTIVATION OF Δ^8-THTRAHYDROCANNABINOL (Δ^8-THC) AT THE 7-POSITION AND MECHANISM OF THE OXIDATION OF 7-HYDROXY-Δ^8-THC TO 7-OXO-Δ^8-THC WITH LIVER MICROSOMES
- IN VITRO METABOLISM OF TETRAHYDROCANNABINOL (THC) BY HUMAN LIVER MICROSOMES. EPOXIDE-DIOL PATHWAY OF THC
- THE PROPERTIES OF UDP-GLUCURONYLTRANSFERASE FOR CANNABINOIDS IN RAT LIVER MICROSOMES
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- EFFECT OF LIVER S9 FROM 3,4,5,3', 4'-PENTACHLOROBIPHENYL-PRETREATED RATS ON THE MUTAGENIC ACTIVITY OF THE VARIOUS CARCINOGENS TOWARD SALMONELLA TYPHIMURIUM TA 98
- Metabolism in Vivo of 3,4,5,3', 4'-Pentachlorobiphenyl and Toxicological Assessment of the Metabolite in Rats
- Acute Toxicity and Inductive Effect on Liver Enzymes of 3,4,5,3', 4'-Pentachlorobiphenyl in Chickens (Regular Presentations) (Proceedings of the 11 th Symposium on Environmental Pollutants and Toxicology)
- STUDIES ON CIS-TRANS ISOMERIZATION OF NITROFURAN DERIVATIVES BY BACTERIAL NITROREDUCTASES
- STUDIES ON THE METABOLISM OF NITROFURAN DERIVATIVES IN BACTERIA : PROPERTIES OF CIS-TRANS ISOMERASES AND NITROREDUCTASES, AND RELATIONSHIP OF THESE ENZYMES
- STUDIES ON ENZYMIC CIS-TRANS ISOMERIZATION OF NITROTHIOPHENE AND NITROBENZENE DERIVATIVES
- Enhanced Elimination of Theophylline, Phenobarbital and Strychnine from the Bodies of Rats and Mice by Squalane Treatment
- PURIFICATION AND CHARACTERIZATION ON 3,4,5,3', 4'-PENTACHLOROBIPHENYL-INDUCIBLE CYTOCHROME P-450 IN CHICKEN LIVER
- Mechanisms of Stimulated Fecal Excretion of Polychlorinated Aromatic Hydrocarbons in Rats
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- IN VIVO METABOLITES OF 3,4,3', 4', -TETRACHLOROBIPHENYL AND THE TOXICOLOGICAL ASSESSMENT IN RATS
- Metabolism of 2,7-Dichlorodibenzo-p-Dioxin in Rats (Regular Presentations) (Proceedings of the 15 th Symposium on Environmental Pollutants and Toxicology)
- Metabolism of Polychlorinated Dibenzofurans (PCDFs) in Rats (Proceedings of the 14th Symposium on Environmental Pollutants and Toxicology)
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- Induction of a High-Spin Form of Cytochrome P-450 by Highly Toxic Polychlorinated Aromatic Hydrocarbons (Proceedings of the 14th Symposium on Environmental Pollutants and Toxicology)
- Cellular Uptake of 2,3,4,7,8-Pentachlorodibenzofuran in the Rat Liver (Proceedings of the 12 th Symposium on Environmental Pollutants and Toxicology) (Regular Presentations)
- ACCUMULATION, EXCRETION AND EFFECTS ON HEPATIC ENZYMES OF POLYCHLORINATED QUATERPHENYL CONGENERS IN RATS
- Intracellular Distribution and Binding to Cytosolic Protein of 2,3,4,7,8-Pentachlorodibenzofuran in the Liver of Rats (Regular Presentations) (Proceedings of the 11 th Symposium on Environmental Pollutants and Toxicology)
- HIGH ACCUMULATION OF 2,3,4,7,8-PENTACHLORODIBENZOFURAN TO HEPATIC MICROSOMES OF RATS
- Extremely High Affinity of 2,3,4,7,8-Pentachlorodibenzofuran for Hepatic Microsomes of Rats (Regular Presentations) (Proceedings of the 10 th Symposium on Environmental Pollutants and Toxicology)
- Effect of 3-Methylcholanthrene-and Phenobarbital-Type Polychlorinated Biphenyls (PCBs) on the Liver Soluble Enzymes of Rats (Regular Presentations) (Proceedings of the 9th Symposium on Environmental Pollutants and Toxicology)
- Enhancement of Reduction Activity of 4NQO in Animals pretreated with 3-Methylcholanthrene-type PCB and PCDF (Regular Presentations) (Proceedings of the 8th Symposium on Environmental Pollutants and Toxicology)
- Enzymatic Hydroxylation of Tetrachlorobiphenyls in Rats
- Metabolism in Vitro of 3,4,3', 4'- and 2,5,2', 5'-Tetrachlorobiphenyl by Rat Liver Microsomes and Highly Purified Cytochrome P-450
- Liver Cytochrome P-450 Isozyme Responsible for the Metabolism of Tetrachlorobiphenyls in Rat (Proceedings of the 16 th Symposium on Environmental Pollutants and Toxicology)
- Inhibition of Cytochrome P-448H Dependent Catalytic Activity by 3,4,5,3', 4'-Pentachlorobiphenyl (Regular Presentations) (Proceedings of the 15 th Symposium on Environmental Pollutants and Toxicology)
- O12-15 Effects of 2, 2', 4', 5, 5'-Pentachlorobiphenyl and 2, 2', 3', 4', 5, 6-Hexachlorobiphenyl on Serum Hormone Levels in Rats and Mice
- O-33 In Vivo Metabolism of 2, 2', 4', 5, 5'-Pentachlorobiphenyl and Its Inductive Activity of Drug-Metabolizing Enzymes : Species Difference between Rats and Mice(Proceedings of the 27th Annual Meeting)
- O-32 2, 2', 4', 5-Tetrabromobiphenyl Metabolite, 3-MeSO_2-2, 2', 4', 5-Tetrabromobiphenyl is a Potent Inducer of CYP2B1/2.(Proceedings of the 27th Annual Meeting)
- Contribution of the 3-Methylsulfonyl Metabolite of 2,2', 4,5,5'-Pentachlorobiphenyl to Heme Metabolic Enzyme Induction by the Parent Compound in Rat Liver(PROCEEDINGS OF 24TH SYMPOSIUM ON TOXICOLOGY AND ENVIRONMENTAL HEALTH)
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- Induction of Hepatic Microsomal Drug-Metabolizing Enzymes by 3-Methylsulfonyl-2,2', 4', 5,5'-Pentachlorobiphenyl in Female Rats (Proceedings of the 23rd Symposium on Toxicology and Environmental Health)
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- In vivo Metabolism of 3,3', 4,4'-Tetrachlorobiphenyl in Rats : Occurrence and Liver-Specific Retention of Methylsulfonyl Metabolite (Proceedings of the 22nd Symposium on Toxicology and Environmental Health)
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- ALTERED THIAMINE PROPYL DISULFIDE METABOLISM IN RATS WITH LIVER INJURY INDUCED BY CARBON TETRACHLORIDE AND D-GALACTOSAMINE
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- MODE OF REACTIONS BETWEEN XANTHINE OXIDASE AND AROMATIC NITRO COMPOUNDS
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