Preparation and Biological Activity of 24-Epi-26,26,26,27,27,27-hexafluoro-1α, 25-dihydroxyvitamin D_2
スポンサーリンク
概要
- 論文の詳細を見る
A new fluorinated analog of vitamin D_2,24-epi-26,26,26,27,27,27-hexafluoro-1α, 25-dihydroxyvitamin D_2,was efficiently synthesized starting from (R)-4-isopropyl-3-propionyl-2-oxazolidinone with high stereochemical control.In all four physiological test systems, the fluorinated vitamin D_2 analog was found to be slightly less active than 1α, 25-dihydroxyvitamin D_3.
- 公益社団法人日本薬学会の論文
- 1995-11-15
著者
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田口 武夫
東京薬科大学薬学部
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田口 武夫
Tokyo College of Pharmacy
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小林 義郎
東京薬科大学薬学部
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Taguchi T
Department Of Pathobiochemistry Faculty Of Pharmacy Meijo University
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伊関 克彦
Daikin Industries, Ltd.,
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大石 訓司
Daikin Industries, Ltd.,
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難波 裕美
Tokyo College of Pharmacy
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小林 義郎
Daikin Industries, Ltd.
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伊関 克彦
ダイキン工業株式会社mec研究所
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Namba Hiromi
Tokyo College Of Pharmacy
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Oishi S
Mec Laboratory Daikin Industries Ltd.
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大石 訓司
Daikin Industries Ltd.
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