Inhibition of Nitrosamine Formation by Inorganic and Organic Salts
スポンサーリンク
概要
- 論文の詳細を見る
Formation of N-nitrosamines from nitrite and secondary amines in acidic solutions was affected by inorganic and organic salts such as chloride, succinate, citrate and tartrate. Formation of N-nitrosodimethylamine at pH 5 was inhibited more effectively than pH 3. The dissociation constant of nitrous acid-nitrite in the solution was decreased by addition of these salts. The salts influenced the nitrous acid nitrite equilibrium to inhibit N-nitrosation of secondary amines.
- 公益社団法人日本薬学会の論文
- 1986-08-25
著者
-
菊川 清見
Tokyo College of Pharmacy
-
加藤 哲太
Tokyo College of Pharmacy
-
加藤 哲太
東京薬科大学薬学部
-
加藤 哲太
東京薬科大学薬学部薬学科
-
飯塚 美恵子
Tokyo College of Pharmacy
関連論文
- P-048 アスコルビン酸、エリソルビン酸によるハンバーグ中の変異原生成の抑制
- Modification of Delipidated Apoprotein B of Low Density Lipoprotein by Lipid Oxidation Products in Relation to Macrophage Scavenger Receptor Binding
- Urinary Excretion of Thiobarbituric Acid Reactive Substances of Healthy Subjects Supplemented with a High Dose of d-α-Tocopherol
- Binding and Uptake of Oxidized Low Density Lipoprotein (LDL) by Macrophage Scavenger Receptors Are Enhanced by Substrate-Bound Fibronectin
- Evidence for Accumulation of Lipid Hydroperoxides during the Aging of Human Red Blood Cells in the Circulation
- A Simple Method for the Assessment of Macrophage Scavenger Receptor-Ligand Interaction : Adherence of Erythrocytes Coated with Oxidized Low Density Lipoprotein and Modified Albumin to Macrophages
- Intraction of Malondialdehyde-Modified Bovine Serum Albumin and Mouse Peritoneal Macrophages
- Formation of Cross-Links and Fluorescence in Polylysine : Soluble Proteins and Membrane Proteins by Reaction with 1-Butanal
- Fluorescent and Cross-Linked Proteins of Human Erythrocyte Ghosts Formed by Reaction with Hydroperoxylinoleic Acid, Malonaldehyde and Monofunctional Aldehydes
- Formation of Direct-Acting Mutagens in Coffee by Treatment with Nitrite
- Formation of a Direct Mutagen, Diazo-N-nitrosoetilefrin, by Interaction of Etilefrin with Nitrite
- Syntheses of 1-(5'-Amino-5'-deoxy-β-D-xylofuranosyl) uracil and Its N_3-Methyl Derivative
- 担子菌Agaricus blazei, Jun-17子実体に含まれる抗変異原性物質及び抗菌性物質
- 杏仁及び桃仁に含有される抗変異原性成分について
- Inactivation of Mutagenic Heterocyclic and Aryl Amines by Linoleic Acid 13-Monohydroperoxide and Methemoglobin
- Studies on the Vilsmeier-Haack Reaction. II. Characterization of Thionyl Chloride-Dimethylformamide Complexes
- Studies on the Vilsmeier-Haack Reaction. III. Synthesis of Cytidine Diphosphate Choline
- 薬学部講義における学生主導型学習法の導入
- 薬学部低学年におけるPBL(Problem-based Learning)教育の試み : その効果と問題点
- Influence of Frying and Baking on Chlorpropham Residue
- 変異原の生成・低減と抗酸化剤(第31回大会シンポジウム「食品中の抗変異原・抗発がん物質のヒトへの有効性」)
- Fluorometric Determination of Malonaldehyde in Oxidized Lipids(Environmental,Chemical)
- Oxidation Products of Linoleate and Linolenate Exposed to Nitrogen Dioxide(Environmental)
- Synthesis of α-Substituted Alkanoic Acids and Inhibition of Platelet Aggregation
- Platelet Aggregation Inhibitors. X. S-Substituted 2-Thioadenosines and Their Derivatives
- Transformation of Adenosine into N_3,3'- and N_3,5'-Cycloadenosines via the Reactions with Sulfuryl Chloride and Thionyl Chloride
- Platelet Aggregation Inhibitors. IX. Chemical Transformation of Adenosine into 2-Thioadenosine Derivatives
- Platelet Aggregation Inhibitors. VIII. 2-Thioadenine Derivatives
- Studies on the Structure of a New Type of Cyclonucleoside, 6,2'-Triazacyclocytidine
- Reaction of Pyrimidine Nucleosides with Sulfuryl Chloride
- Alteration of 5-Chloropyrimidine Nucleosides in Alkaline Media
- Platelet Aggregation Inhibitors. V. Pyrimidine Derivatives, Indole Derivatives, Benzothiophenes, and Benzoquinolizine Derivative
- Effect of Plasma pH on Stability and Capacity of Aggregation of Platelets
- Platelet Aggregation Inhibitors. I. Hydroxylamine : A Potent Inhibitor of Platelet Aggregation
- Synthesis of a Nucleotide Coenzyme, CDP-Choline
- Reactions of Methyl Iodide on 2,2'-Anhydro-1-(β-D-arabinofuranosyl)-uracil and 2,3'-Anhydro-1-(β-D-xylofuranosyl) uracil
- Reaction of Hydrogen Halides on 2,3'-Anhydro-1-(β-D-xylofuranosyl) uracil
- Contribution of Alkadienals and/or Alkenals in the Ferric and Ferrous Ion-Enhanced TBA-Reactivity of Oxidized Oils
- Is the Thiobarbituric Acid-Reactivity of Blood Plasma Specific to Lipid Peroxidation?
- Polysines Modified with Malonaldehyde, Hydroperoxylinoleic Acid and Monofunctional Aldehydes
- Studies on Peroxidized Lipids : Fluorescent Products Derived from the Reaction of Unsaturated Fatty Acids and Methylamine
- P-53 ハンバーグ加熱時における変異原物質の生成は糖添加量により促進あるいは阻害される
- Effect of tert-Butylhydroquinone (TBHQ) on the Formation of Nitrosamines in the Reaction of Secondary Amines with Nitrite
- フリーラジカルを経由する変異・発がん物質の生成と発現 : 第11回公開シンポジウム : 環境変異原の活性発現と抑制の化学的機構
- O-7 ヘテロサイクリックアミン変異原生成に対するヒドロキシフラノンとアスコルビン酸の影響
- P-60(O-5) コーヒーに含まれるベンゼン活性代謝物
- ^P-Postlabeling Detection of DNA Base Adducts in Mice Induced by 4-(Hydroxymethyl) benzenediazonium Salt, a Carcinogen in Mushroom Agaricus bisporus
- 食品におけるフリーラジカル性変異原の生成とその阻止
- Thiamine Is a Precursor of DNA Strand Breakage and Mutagenic Substance (s) When Mixed with Nitrite
- セサモールから生成するニトロソセサモールの変異原性とDNA鎖切断作用
- Generation of a Carbon-Centered Radical with DNA-Breaking Activity from Mutagenic Fluorene-2-Diazonium Salt
- 2,2'-Azobis(2-amidinopropane)dihydrochloride(AAPH)から生成する炭素ラジカルの変異原性
- Examination of the Extraction Methods and Re-evaluation of Blue Fluorescence Generated in Rat Tissues in Situ
- Characteristics of Fluorescence Formed by the Reaction of Proteins with Unsaturated Aldehydes, Possible Degradation Products of Lipid Radicals
- Formation of Fluorescent Products in the Reaction of Butyraldehyde and Methylamine as a Model of the Reaction of Oxidized Lipids and Proteins
- Studies on Peroxidized Lipids. II. Fluorescent Products Relevant to Aging Pigments derived from Malondialdehyde and Methylamine
- Variations in the Level of Urinary Thiobarbituric Acid Reactant in Healthy Humans under Different Physiological Conditions
- 薬学部低学年における基本課題と自由臨床課題の併用学習の効果
- Studies on the Antioxidants. XVI. Synergistic Reaction between Butylated Hydroxyanisole and Butylated Hydroxytoluene in Hydrogen Donation to 2,2-Diphenyl-1-picrylhydrazyl
- Studies on the Antioxidants. XIV. : Reaction of Sesamol with Hydrogen Peroxide-Peroxidase
- Interaction of Hemoglobin A with Sesamol and Polyphenolics
- Studies on the Antioxidants. XII. Combination Effects of Antioxidants on the Reduction of Ferric Ions
- Studies on the Antioxidants. XIII. Hydrogen Donating Capability of Antioxidants to 2,2-Diphenyl-1-picrylhydrazyl
- The Butylated Hydroxyanisole-Nitrite Reaction : Effects on N-Nitrosodimethylamine Formation in Model Systems
- C-Nitrosation of Sesamol and Its Effects on N-Nitrosamine Formation in Vitro
- Oxidation of Sesamol Dimer by Active Species produced in the Interaction of Peroxide and Hemoglobin
- Transformation of Hemoglobin by Various Peroxides in Vitro
- Studies on the Antioxidants. XV. Combination Effects of Butylated Hydroxyanisole, Butylated Hydroxytoluene and Their Analogs on Hydrogen Donation to 2,2-Diphenyl-1-picrylhydrazyl
- Studies on Peroxidized Lipids. III. Fluorescent Pigments derived from the Reaction of Malonaldehyde and Amino Acids
- Factors Influencing the Autoxidation of Hemoglobin A
- Properties of Conjugated Schiff Bases of Malonaldehyde
- Role of Heme Compounds in the Erythrocyte Membrane Damage Induced by Lipid Hydroperoxide(Biological)
- Studies on the Antioxidants. XX. The Effect of Butylated Hydroxytoluene on tert-Butylhydroperoxide-Induced Oxidation of Butylated Hydroxyanisole
- Inhibition of Nitrosamine Formation by Inorganic and Organic Salts
- Formation of Nitrosamines in Organic Solvents and Aqueous Systems Containing Organic Solvents
- Fluorescence of 1,4-Dihydropyridine Derivatives Relevant to Age Pigments(Environmental,Chemical)
- Studies on the Intermediates of Methemoglobin by the Use of a Cross-Linking Agent
- Studies on Peroxidized Lipids. I. Interaction of Malondialdehyde with Secondary Amines and Its Relevance to Nitrosamine Formation
- Cross-Linking Reaction of a valency Asymmetrical Hybrid Hemoglobin Formed in a Mixture of Hemoglobin A and Methemoglobin
- セルフメディケーション教育とOTC医薬品