Formation of Cross-Links and Fluorescence in Polylysine : Soluble Proteins and Membrane Proteins by Reaction with 1-Butanal
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概要
- 論文の詳細を見る
The reaction of polylysine and 1-butanal afforded 2-ethyl-2-hexenal, an aldol condensation and dehydration product of 1-butanal. 1-Butanal and 2-ethyl-2-hexenal were able to form fluorescence in polylysine, bovine serum albumin and erythrocyte membrane proteins. They were able to cross-link polylysine, hemoglobin, erythrocyte membrane proteins and isolated spectrin. Formation of cross-links by these aldehydes depended of the kind of protein. The ability of the proteins to form cross-links may reflect the contents of functional groups respomsible and the quaternary structures of the proteins. 1-Butanal and 2-ethyl-2-hexenal may participate in the formation of cross-links and fluorescence by interaction with amino groups in the proteins.
- 社団法人日本薬学会の論文
- 1988-02-25
著者
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別府 正敏
Tokyo College of Pharmacy
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菊川 清見
Tokyo College of Pharmacy
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別府 正敏
東京薬大 公衆衛生学
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別府 正敏
東京薬科大学
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別府 正敏
東京医科大学 小児科学
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岩田 篤史
Tokyo College of Pharmacy
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Beppu M
Tokyo College Of Pharmacy
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Beppu Masatoshi
School Of Pharmacy Tokyo University Of Pharmacy And Life Sciences
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