Synthesis of α-Substituted Alkanoic Acids and Inhibition of Platelet Aggregation
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概要
- 論文の詳細を見る
A series of 4-substituted phenyl-(A, B) and 5-substituted 2-thienyl-(C) acetic acid derivatives were synthesized. Inhibitory activity of collagen-induced rabbit platelet aggregation of 29 compounds including A, B, C and the intermediate compounds of them was studied. Compounds (A-18,B-21 and -27) were inhibitory against platelet aggregation and the most potent compound (B-21) was more effective than aspirin.
- 公益社団法人日本薬学会の論文
- 1978-03-25
著者
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菊川 清見
Tokyo College of Pharmacy
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菊川 清見
Research Laboratory, Division of Fermentation and Chemical Products, Kohjin Co., Ltd.
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吉村 昌治
Research Laboratories, Kohjin Company, Ltd.
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高橋 進
Research Laboratories, Kohjin Company, Ltd.
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川俣 章
Research Laboratories, Kohjin Company, Ltd.
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末広 日出男
Research Laboratories, Kohjin Company, Ltd.
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青木 旦治
Research Laboratories, Kohjin Company, Ltd.
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吉村 昌治
Research Laboratories Kohjin Company Ltd.
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末広 日出男
Research Laboratories Kohjin Company Ltd.
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青木 旦治
Research Laboratories Kohjin Company Ltd.
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川俣 章
Research Laboratories Kohjin Company Ltd.
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高橋 進
Research Laboratories Kohjin Company Ltd.
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