Studies on the Antioxidants. XV. Combination Effects of Butylated Hydroxyanisole, Butylated Hydroxytoluene and Their Analogs on Hydrogen Donation to 2,2-Diphenyl-1-picrylhydrazyl
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Combination effects of butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT) and their analogs on hydrogen donation to 2,2-diphenyl-1-picrylhydrazyl (DPPH) were investigated. A synergistic effect was observed when 2,6-di-tert-butylphenol derivatives were combined with 4-methoxyphenol derivatives such as BHA and 4-methoxyphenol. This effect might arise from the regeneration of 4-methoxyphenol derivatives from possible intermediates formed from DPPH and these phenols, with enhanced loss of the 2,6-di-tert-butylphenol derivatives. The formation of the cross coupling compound from a pair in combination might decrease the regeneration of the phenols and thus influence the synergistic effect.
- 公益社団法人日本薬学会の論文
- 1981-10-25
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