Chemical Transformation of Uronic Acids leading to Aminocyclitols. II. Synthesis of Hexaacetyl-streptamine from N-Acetyl-D-glucosamine

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概要

• 論文の詳細を見る

• By employing the oxidative decarboxylation reaction using lead tetraacetate and successive nitromethane cyclization reaction in the reaction sequence, N-acetyl-D-glucosamine (11a) has been converted to hexaacetyl-streptamine (20a) in 8% overall yield. It has been also suggested that the present transformation would provide a versatile method for preparation of aminocyclitols from various types of uronic acids.

• 公益社団法人日本薬学会の論文
• 1978-12-25

著者

• 吉川 雅之

  Faculty of Pharmaceutical Sciences, Osaka University

• 北川 勲

  Faculty Of Pharmaceutical Sciences Osaka University

• 門田 明子

  Faculty Of Pharmaceutical Sciences Osaka University:(present Address)department Of Chemistry School

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