CAPILLARTEMISIN A AND B, TWO NEW CHOLERETIC PRINCIPLES FROM ARTEMISIAE CAPILLARIS HERBA

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概要

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• By monitoring with a choleretic activity test for rat-duodenum, two new choleretic principles named capillartemisin A (1) and B (2) were isolated from Artemisiae Capillaris Herba ("Inchinko" in Japanese, the aerial part of Artemisia capillaris Thunb.), and their structures were determined on the basis of spectral evidence and by a synthesis of the methyl ester of 1 (1a). Capillartemisin A (1) and B (2) showed more potent and lasting choleretic activity than sodium dehydrocholate and the other hitherto identified choleretic principles of "Inchinko". A new flavonoid isoarcapillin (6) was also chemically elucidated.

• 公益社団法人日本薬学会の論文
• 1983-01-25

著者

• 山原 條二

  Kyoto Pharmaceutical University

• 吉川 雅之

  Faculty of Pharmaceutical Sciences, Osaka University

• 北川 勲

  Faculty Of Pharmaceutical Sciences Osaka University

• 福田 陽一

  Faculty of Pharmaceutical Sciences, Osaka University

• 吉原 実

  大阪大学薬学部

• 吉原 実

  Faculty of Pharmaceutical Sciences, Osaka University

• 福田 陽一

  Kyoto Pharmaceutical University

• 福田 陽一

  小城製薬株式会社研究所

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